Using Songbirds as a Model for understanding learning and linguistic disabilities in Autism

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Using Songbirds as a Model for understanding learning and linguistic disabilities in Autism
Presentation for a course on Developmental Neurobiology

Resources:

Baran, Nicole M., et al. “Early Life Manipulations of Vasopressin-Family Peptides Alter Vocal Learning.” Proceedings of the Royal Society B: Biological Sciences, vol. 284, no. 1859, 19 July 2017, doi:10.1098/rspb.2017.1114.

Breedlove, S. Marc. Foundations of Neural Development. Sinauer Associates, Inc. Publishers, 2017.

Condro, Michael C., and Stephanie A. White. “Distribution of Language-Related Cntnap2 Protein in Neural Circuits Critical for Vocal Learning.” Journal of Comparative Neurology, vol. 522, no. 1, Jan. 2014, pp. 169–185., doi:10.1002/cne.23394.

Dicicco-Bloom, E., et al. “The Developmental Neurobiology of Autism Spectrum Disorder.” Journal of Neuroscience, vol. 26, no. 26, 28 June 2006, pp. 6897–6906., doi:10.1523/jneurosci.1712-06.2006.

Panaitof, S. Carmen “A Songbird Animal Model for Dissecting the Genetic Bases of Autism Spectrum Disorder.” Hindawi, vol. 33, 16 Aug. 2012, doi:10.3233/DMA-2012-0918.

Panaitof, S. Carmen, et al. “Language-relatedCntnap2gene Is Differentially Expressed in Sexually Dimorphic Song Nuclei Essential for Vocal Learning in Songbirds.” The Journal of Comparative Neurology, vol. 518, no. 11, 1 June 2010, pp. 1995–2018., doi:10.1002/cne.22318.

Teramitsu, I., et al. “Parallel FoxP1 and FoxP2 Expression in Songbird and Human Brain Predicts Functional Interaction.” Journal of Neuroscience, vol. 24, no. 13, 31 Mar. 2004, pp. 3152–3163., doi:10.1523/jneurosci.5589-03.2004.

Shi, Zhimin, et al. “MiR-9 Regulates Basal Ganglia-Dependent Developmental Vocal Learning and Adult Vocal Performance in Songbirds.” ELife, vol. 7, 18 Jan. 2018, doi:10.7554/elife.29087.

[FirstPersonSciencePodcast]

Great stuff! It's super admirable that you're putting out such well thought-out content on science communication. We need more great scicomm devoted to the intricacies the brain and its functions. It affects us all and is fascinating science. Cant wait to see more!

[farciao]

Thank you for this video. My 19 y.o. son has ASD has recently been found to have FOXP1. We are also dealing with PANS/PANDAS. I love to learn as much as I can about all of these things. P/P also attacks the Basal Ganglia.