DNA major and minor grooves

My teaching project page: Biochemistry Literacy for Kids

Proteins and other molecules that bind DNA specifically recognize either the major or minor groove. This is a short video that shows the differences between the major and minor grooves. Keep in mind that the chirality of the 1', 3', and 4' carbons of the deoxyribose confer asymmetry to the double helix and give rise to the major and minor groves.

[Abdullah-krkv]

🎯 Key Takeaways for quick navigation:

00:03 *🧬 DNA Major and Minor Grooves Overview*
- Explanation of major and minor grooves in DNA structure,
- Major groove depicted in pink, minor groove in blue,
- Major groove larger than the minor groove.
00:33 *🏛️ Orientation of Deoxyribose in Major and Minor Grooves*
- Deoxyribose orientation in major groove: ring oxygen up, resembling the Statue of Liberty with the torch,
- Deoxyribose orientation in minor groove: ring oxygen down, akin to an upside-down Statue of Liberty,
- Consideration of directionality (five prime to three prime) in viewing polynucleotides.
01:15 *🔄 Complementary Backbone Orientation in Major and Minor Grooves*
- Complementary orientation of deoxyribose in major groove of the right backbone compared to the left backbone,
- Contrast in deoxyribose orientation in minor groove of the right backbone compared to the left backbone,
- Emphasis on opposite orientations for complementary backbones.

Made with HARPA AI

[GuilledelCastillomusica]

I found this looking for a funky groove to play along with bass... Interesting, thank you :)

[willontheregular]

Love this video my pag is gonna be next level 13B gang

[sccm]

Good video but I really don't know exactly what my professor wants us to know about the minor and major groove.

[samirmanjothi]

What are the fuction of major and minor groove?

[gamingpoint]

Can anyone help what is blue, red, white, yellow balls means i mean which element?

[farshidrazavi]

please can you put the Read Transcript ?

[erenk]

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[Medhat-clay]

Very confusing and doesn’t explain it at all, not helpful