SERS for Trace Level Virus Detection

In this video, we demonstrate how our proprietary surface-enhanced Raman spectroscopy (SERS) substrates enhance Raman signal to detect antibody samples from SARS-CoV-1 and -2 proteins.

With demand for faster, more accurate diagnostics, medical and life sciences pros require analytical insights and tools that are smarter, simpler and more robust. Learn how SERS can be implemented into portable systems developed by manufacturers for virus detection and testing.

What Is Raman Detection?

Raman detection is a comprehensive chemical analysis technique where laser light interacts with a sample's molecular properties. Many wavelengths will match and exit the specimen unchanged, yet one photon in a million will spread differently. Raman detection identifies these disparities in scattering patterns.

Benefits of SERS for rapid detection of COVID-19 antibodies

Raman, a laser interrogation technique, helps speed up the detection of COVID-19 antibodies. Using the Ocean Insight QE Pro Raman+ high-performance spectrometer, we help customers push the limits of spectral detection.

What Tools Are Being Used?

This demonstration begins with the QE Pro 785-nanometer spectrometer with high resolution and sensitivity. The QE Pro delivers high-performance capability in low-light scenarios. During the process, the laser connects to a holder for the affordable SERS-AU-5. The proprietary SERS substrate contains embedded gold nanoparticles to identify otherwise undetectable Raman shifts.

What Is Antibody Detection and How Is It Used?

Antibody detection determines who has overcome a viral infection by identifying the presence of specialized proteins. Humans produce these proteins as an immune response, and their presence helps health care professionals trace exposure and spread within a community. The SERS detection method produces quick results for more immediate spread-stopping measures.

About Ocean Insight?

Ocean Insight designs and manufactures custom measurement equipment and accessories. Our modular light-measuring equipment serves industries worldwide across many fields, including biomedical, environmental, research and manufacturing. Collaborate with us to create a custom solution for accurate, comprehensive measurements that meet your organization's needs.

Timestamps

[0:04] Traditional detection methods and their limitations
[0:15] Raman — a laser interrogation technique
[0:41] Testing Raman SERS setup to detect SARS-CoV-1 and -2 proteins
[0:55] Setup included in test
[2:25] Detection results

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