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019 | Are Lipid Nanoparticles in mRNA tech - the hidden danger? | Christie Grace
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Christie Grace is a consultant in biotechnology specifically on recombinant antibodies, CRISPR, mRNA, gene synthesis & Quality control. On this episode we discuss Lipid Nanoparticles (LNP) - and how they relate to mRNA technology as the delivery mechanism. We dive into the known adverse outcomes related to the LNP's with regards to clotting, damage to endothelial cells, fertility and more as well as how this was known to the CDC and NIH for years prior. The freeze-thaw process is also out to be questioned due to known ways this degrades the LNP's.
0:45 Intro
04:30 What is it about the mRNA tech that's so different? What about in the lab?
10:30 Why is the timeline questionable for the trials?
12:00 What is mRNA, how is it produced?
23:45 What & Why are LNP's important (lipid nano particles)
41:00 mRNA fragmentation within batches/vials
47:15 Could fragmentation be an accident
53:00 Freeze thaw
54:30 Ribosomal overload
1:00:00 Real life freezee thaw issues (data at the 53 min mark)
1:09:00 Does the initial trial pass the sniff test?
1:18:30 What does this mean for the public?
1:29:00 Where does this all end?
1:46:50 Top tips to stay aware
1:54:40 Where to find Christie
Follow Christie
Substack
Follow me
What are Ionizable Lipids (for use in Lipic Nano Particles)
Degredation of LNP
Safety data sheets
LNP Oxidative stress & toxicity (clots, cancer inducing etc.)
LNP Reproduction
Misfolded proteins
Aussie TGA specific batches and allocations
Japan foreign substances
Freeze thaw
Spike found in brain & heart tissue
"Dansen met Janssen" (You'll have to translate the page)
What's spike
Safety of LNP mRNA rat/monkey
Circulating spike protein
Coagulation triggered by positively charged surfaces
Phosphatidylethanolamine & coagulation with VLDL
Mouse models and human lipoprotein suitability
Naturally occurring cholesterol analogues in LNP
Mechanisms for DVT & Management
Plasma lipids & Clotting
Shot may trigger thyroid autoimmunity
Phosphatidylethanolamine
Clotting and lipids
Endothelial cell dysfunction
YouTube:
Rumble:
0:45 Intro
04:30 What is it about the mRNA tech that's so different? What about in the lab?
10:30 Why is the timeline questionable for the trials?
12:00 What is mRNA, how is it produced?
23:45 What & Why are LNP's important (lipid nano particles)
41:00 mRNA fragmentation within batches/vials
47:15 Could fragmentation be an accident
53:00 Freeze thaw
54:30 Ribosomal overload
1:00:00 Real life freezee thaw issues (data at the 53 min mark)
1:09:00 Does the initial trial pass the sniff test?
1:18:30 What does this mean for the public?
1:29:00 Where does this all end?
1:46:50 Top tips to stay aware
1:54:40 Where to find Christie
Follow Christie
Substack
Follow me
What are Ionizable Lipids (for use in Lipic Nano Particles)
Degredation of LNP
Safety data sheets
LNP Oxidative stress & toxicity (clots, cancer inducing etc.)
LNP Reproduction
Misfolded proteins
Aussie TGA specific batches and allocations
Japan foreign substances
Freeze thaw
Spike found in brain & heart tissue
"Dansen met Janssen" (You'll have to translate the page)
What's spike
Safety of LNP mRNA rat/monkey
Circulating spike protein
Coagulation triggered by positively charged surfaces
Phosphatidylethanolamine & coagulation with VLDL
Mouse models and human lipoprotein suitability
Naturally occurring cholesterol analogues in LNP
Mechanisms for DVT & Management
Plasma lipids & Clotting
Shot may trigger thyroid autoimmunity
Phosphatidylethanolamine
Clotting and lipids
Endothelial cell dysfunction
YouTube:
Rumble:
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