Spotlight on Methods and Tools: ROBINS-I

This webinar was presented on September 27, 2017.

ROBINS-I: A tool to appraise the risk of bias in non-randomized studies of interventions

The ROBINS-I tool can be used to appraise non-randomized studies comparing the health effects of two or more interventions. This includes a number of observational study designs such as cohort studies, quasi-randomized trials, and case-control and cross-sectional studies. Join us for a webinar to learn about the ROBINS-I!

This tool was developed by a team at the University of Bristol.

How can the ROBINS-I help you?

Many types of study designs that evaluate interventions in public health do not use randomization. The ROBINS-I provides a single process that can be used to appraise these different types of evidence. This supports the use of evidence to formulate recommendations and develop public health actions.

The ROBINS-I consists of a seven domain appraisal framework. The tool also offers a number of explanations for ratings, terms, definitions and theory.

This webinar includes an overview of the ROBINS-I by its developers, Jonathan Sterne and Julian Higgins and a presentation by users Judy Brown and Duvaraga Sivajohanathan.

The National Collaborating Centre for Methods and Tools is funded by the Public Health Agency of Canada and affiliated with McMaster University. The views expressed herein do not necessarily represent the views of the Public Health Agency of Canada.

NCCMT is one of six National Collaborating Centres (NCCs) for Public Health. The Centres promote and improve the use of scientific research and other knowledge to strengthen public health practices and policies in Canada.

[hanadiam]

Hello and thanks for sharing, in 35:20 the presenter said that they gave a course that explains every domain, can anyone please send the link for me? I need it urgently please

[jmvm]

Hi, could you please explain what is confounding domains with an example?How to answer for preliminary consideration of confounders?What do you meant by co-intervention?Is there any video regarding how to do these question and answer with example?How many answers should be no to get result as serious ROB? Is there any scores to get final results like.. if all 7 answer is no, it is considered to be having serious ROB?

[aaronpaulbaliga]

Can I use the ROBINS-I in an experimental study?

[leiremartin]

Should I use ROBINS-I for case control studies?

[davidbui]

Is it possible to get a copy of the Checklist discussed by the reviewer at 1:02:41? I am writing a systematic review and would find that extremely useful.

[greenba]

Only confounding and selection bias was illustrated. The selection bias part was very confusing.

[Estreas]

Hello there, can this tool be used in cohort single-arm studies (non-randomised)?

[yankierpijeiraperez]

Hi @NCCMT, I am appraising non-randomised interventions using this guidance. However, I came across a few Post-marketing surveillance (PMS) studies, where different medications or drug regimes (interventions) are compared through a series of surveys and clinical evaluations. Can this guidance be used to analyse such papers (PMS), considering they are not proper interventions?

[fatemehhedayat]

Can this tool be used for retrospective studies? Thanks.