SIBO Updates and Q&A with Dr Mark Pimentel

Dr. Siebecker and co-host Shivan Sarna's annual SIBO research update with Dr. Mark Pimentel, SIBO researcher and expert. He shares a slide presentation followed by Q&A.

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About the Speakers:
Dr. Allison Siebecker has specialized in SIBO since 2010. She is the GastroANP 2021 Lifetime Achievement Award winner, teaches Advanced Gastroenterology at NUNM, co-created and was the former Medical Director of the SIBO Center for Digestive Health at NUNM, and is an award-winning author.

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DISCLAIMER: This video is not intended to provide diagnosis, treatment, or medical advice. Content is for informational purposes only. Please consult with a healthcare professional regarding any medical or health-related diagnosis or treatment options. Information in this video should not be considered as a substitute for advice from a healthcare professional. References to and statements made about specific products in this video are not to diagnose, treat, cure, or prevent disease.

[maxrymsha]

Briliant infromation! Thank you very much, Dr Mark Pimentel and your team for all the efforts you put into the research and Dr. Allison Siebecker for this amazing podcast!

[bertwoodshack]

What can I say? that was an excellent interview all 3 of you are amazing. 🏆👏

[owenyonce]

The summation of the ibs portion of his presentation is that the majority of ibs (at least ibs-d) is of the "post infectious" variety and those patients clearly have the antibodies present and an animal model runs parallel to the human studies. He alludes to the target of removing these antibodies from the body.

What is the target date for an approved drug/therapy to remove these antibodies? To me, this is one of the most important questions and I'm surprised it wasn't asked.

[angiecanada]

Optimism has been renewed! Thank you for this release of info in this video. I’ve watched it the day it was uploaded and have rewatched it several times. Can hardly stand the wait for the release of treatment protocols this fall!!

[TheWillfs]

Incredible that he mentioned "IBS was considered a disease of hysterical women"...which is TRUE!! Crazy to think how far we have progressed since then thanks to this man, unbelievable work.

[davidalexander]

thank you for this great up to date information, Dr Pimentel you're the man

[bertwoodshack]

Excellent interview well done ladies 👏

[guitarlearningtoplay]

Dr. Pimentel did a study/paper that said that lactose intolerant patients have an increase of Hydrogen on breath tests. So how is it not a false positive if someone takes the test with lactulose (the most used sugar)? And glucose does not seem like a good alternative either since it is rapidly absorbed before it makes it even half way into the small intestine. What is the alternative?

[andrewlittle]

After implementing an elemental diet for the 14 days, and assuming after another 14 days, you declare victory, does the motility return much like the ideal microbiome flora that was mentioned?

[steelergyrl]

Thank you for all this info. I've been recently diagnosed with SIBO. How can I be considered as a candidate for the upcoming study this fall?

[AnneDupere-vbou]

In the whole subject of SIBO treatment. Why do we treat all hydrogen SIBO the same way ( for example) when we don’t even know which specific bacteria we are dealing with?

Usually we match the right antibiotic to the bacteria we are trying to kill, no ?

[annettemarquez]

I tested positive for methane and I've been having diarrhea but I also have mild constipation, not too terrible though. Could the diarrhea be caused by post infection IBS?

[KaMusic]

What does it mean if after a 2-week elementary diet the test shows lower hydrogen but much higher methane than it was before the treatment?

[philipmicrebus]

If anti-vinculin can cause SIBO and anti-vinculin goes down slowly. Would trying to wipe the SIBO be pointless? Even if you clear the SIBO, would the anti-vinculin cause SIBO to return? Or does curing the SIBO help lower anti-vinculin faster?

[ellenmykkanen]

Is anyone providing information on SIBO in Gastric Bypass patients who are several years out of surgery? All I can find is notes that it is a risk factor and happens a lot

[mariabensonrozo]

Thank you!! Could this information be delivered to gastroenterologist in Wisconsin? They go f have a clue!

[ClockDesignCo]

Love listening to this guy. But he's looking more and more like Jeff Goldblum every day

[druguryavuzcan]

I wonder what dose of n-acetyl cysteine is administered with rifaximin in sibo cases?
I don't think he mentioned the dose during the broadcast.

[LadyJ.T]

They don’t get enough recognition!!! 👏 👏

[thomaswopelka]

Thank you so much for your science.

Is it actually common/possible that methan producers coexist with sulfur producers or is this rare?

I have a constant methane level around 16 ppm and a constant H2 around 8 ppm for 3 hrs in a lactulose breath test. There is no rise at the end. H2S is not measured. Would you say it is likely that there are some H2S producers as well or not with these curves?

Symptoms are constant bloating and irritable bowel with some pricking pain. Sometimes itchy skin etc.
I was also diagnosed with a few small aphthous spots in the terminal illeum.