Mastering In vitro Release Testing: A Step by Step Guide

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Unlock the secrets of In-vitro Release Testing (IVRT) with our comprehensive step-by-step guide! In this 10-minute video, we delve into the vital aspects of IVRT method development, including receptor media selection, membrane choice, and the critical use of the Franz diffusion cell. We’ll walk you through selecting appropriate time points, speeds, and the essential process of mounting the membrane for optimal results.

Discover the intricacies of IVRT method validation, as well as how to conduct an IVRT study for Bioequivalence. Learn to calculate slopes and interpret results, including the 90% confidence interval of T/R ratios.

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#InVitroReleaseTesting #PharmaceuticalDevelopment #IVRT #Bioequivalence #FranzDiffusionCell #PharmaScience

OUTLINE:

00:00:00 Understanding In-Vitro Release Testing (IVRT)
00:01:08 Selecting the Right Receptor Media
00:02:11 Choosing the Appropriate Membrane
00:03:11 Utilising Franz Diffusion Cells
00:04:16 Determining Time Points and Speed
00:05:19 Mounting a Membrane on a Franz Diffusion Cell
00:06:20 Validating the IVRT Method
00:07:31 IVRT in Bioequivalence Testing
00:08:30 Analysing and Interpreting IVRT Results
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