8 Side Effects of the Ketogenic Diet + How to Reverse Them

8 Side Effects of the Ketogenic Diet + How to Reverse Them - Thomas DeLauer

Skin Health - Skin dries out with dehydration (Fix with Collagen)

A study published in the International Journal of Molecular Sciences looked at the effects of collagen peptides on skin epidermal moisturization after ultraviolet B irradiation-induced skin dehydration

Hairless mice were orally administered CP at two doses (500 and 1000 mg/kg) for nine weeks, and the dorsal skin was exposed to UVB.

Oral administration of CP increased skin hydration and decreased wrinkle formation compared to the UVB-irradiated group.

Treatment of CP increased the mRNA and protein expression of hyaluronic acid synthases (HAS-1 and -2) concomitant with an increased hyaluronic acid production in skin tissue

The expression of hyaluronidase (HYAL-1 and 2) mRNA was downregulated in the CP-treated group.

In addition, the protein expression of skin-hydrating factors, filaggrin and involucrin, was upregulated via oral administration of CP

In summary, these results show that oral administration of CP increases hyaluronic acid levels, which decreases during UVB photoaging

Fatigue - Mag ATP

Gluconeogenesis increases on keto, demanding more ATP

ATP (adenosine triphosphate), the main source of energy in cells, must be bound to a magnesium ion in order to be biologically active - what is called ATP is often actually Mg-ATP

Loss of Anaerobic Power

The bulk of ATP for anaerobic exercise comes from glycolysis - the glycolytic process requires that muscle cells breakdown glycogen to glucose via the glycogen phosphorylase pathway

One possible mechanism for reduced anaerobic capacity may be attributed to the LCD-induced keto-acidosis, which was reflected in the present study by reduction of blood pH.

It is well established that anaerobic glycolysis is limited by acidosis via inhibition of the rate limiting enzyme, phosphofructokinase

PFK-1 catalyzes the important "committed" step of glycolysis, the conversion of fructose 6-phosphate and ATP to fructose 1,6-bisphosphate and ADP

Headaches

Dehydration

When the body is dehydrated, the brain can temporarily contract or shrink from fluid loss - this mechanism causes the brain to pull away from the skull, causing pain and resulting in a dehydration headache.

Once rehydrated, the brain plumps up and returns to its normal state, relieving the headache.

Also believed that blood vessels in the head may actually narrow in an attempt to regulate body fluid levels - this would make it harder for oxygen and blood to get to the brain, a headache results

Believed that a keto diet would attenuate migraines due to ketones being able to counteract the neuroinflammation involved in migraines

Per The Journal of Headache and Pain:

Migraineurs were found and enrolled in a dietician clinical setting. All clinical data were recorded before the diet initiation and, blind to neurologist, subjects were divided in two subgroups: KD and SD followers. After a one month period of diet, patients were re-evaluated for comparisons.

Headache frequency and drug consumption was reduced during the observation period, but only in KD group. Responder rates in KD group (52 subjects) were higher than 90% in terms of attack frequency and drug consumption in the month of observation, while SD group (56 subjects) has no effect.

Responder rate: 90% of those in the KD group saw reductions in migraines

Muscle Stiffness (Omega 6 Related)

Constipation

Dehydration & electrolyte deficiency is also a cause of constipation and is a problem people on the keto diet face.

Our stools are largely composed of water - 75% of the feces is composed of water, while only 25% is attributed to solids

Keto Breath

The liver breaks down acetone - the smell can vary, but it usually has a fruity (like the smell of rotten apples) smell – usually likened to the smell of nail varnish remover (acetone is a chemical in nail polish remover)

Keto Rash - Neutrophilic Infiltration

Ketone bodies are thought to accumulate around blood vessels, leading to a predominantly neutrophilic inflammation

The ketones subsequently enter the cells, leading to alterations in intracytoplasmic cellular processes [note: “intracytoplasmic” = inside the cytoplasm, which is part of the inside of a cell]

[viking]

I was on Atkins 15 or so years ago to help fight migraines out of medical control. So I tried Atkins to try something, the migraines stopped completely within the week. Also lost 40 lbs (wasn't a goal) but the real side effects surprise was attraction of woman and my new girlfriend broke my heart so I ate at her I got resick and fat and no attraction. So 10 years later I got a borderline diabetic warning and that snapped me to return to low carb. And in a month my Dr. At the VA. Said I was no longer pre-diabetes. Yes the attraction is back, 55lbs are gone, naps are gone. At 73 y/o I'm so much healthier and that's great to know. So pork rinds!

[soulheal]

1. 0:49 Fatigue - - Mg
2. 1:55 Loss strength - - normal
3. 3:17 Headaches - - hydration
4. 4:24 Skin health - - hydration, collagen peptide
5. 7:00 Constipation - - hydration
6. 7:43 keto breath - - go with time
7. 8:48 muscle and joint stiffness - - omega 3 / more fat
8. 9:55 keto rash - - go with time

[DanaNourie]

Because of Keto my migraines went from 15 to 2 a months and daily headaches went away completely. My energy is amazing. I feel 15 years younger. Literally. One year on Keto. Thomas is the Keto

[macshort]

Thomas, I just want to say thank you... I have struggled with my weight all of my life... I stumbled upon your videos and got stated on the Keto lifestyle 5 weeks ago... starting weight of 313, as of this morning I am at 280 (your starting point) down 33 pounds in 5 weeks... anyone reading this IT WORKS!!! I am continuing to watch your videos and learning more every day !!! Again, thanks so much for helping me reaching a healthy life !!! A Lessing (weight wise) huge fan lol!!!

[sharoncousins-clarke]

I've always suffered from headaches and don't get them since I've been on keto

[mollywest]

I really appreciate your respectful, calm tone of voice throughout the video. I’m so tired of fitness people screaming through the whole video and being condescending to viewers who are trying to better themselves

[samanthabrooks]

Since starting your keto challenge I have not had a single migraine. Thank you!

[cjh]

He speaks well and his message is clear and easy to follow.

[dilcypetruzziello]

Can I see a video on how to build a proper keto plate of food.

[mylowcarb]

My Ketodiet Journey1 second ago
Thank you doc.what I did is I drink water with himalayan salt and eat right food I have a also channel I post some of my low carbs recipes

[christophermcowen]

Im a month in and i cant believe how awesome i feel. I would always feel heavy and almost weighted down. But since i watched a video of yours i decided that its time for a change. I havent suffered any side effects and i've lost about 22lbs thus far. Cant wait to see where i am in 5 more months.

[DeoAlDente]

Thanks for your work. Keto is saving my life. I'm 23. Used to be 130 kg. I've lost 20 kilos this summer only by keto & swimming.

[magneticflux]

I got all of these except the rash. The headaches are the worst....
After keto flu I rarely ever get headaches.

[Xteriorr]

I start my keto journey on Monday and I can’t wait to finally get this weight off

[abdullahjarallah]

1- Fatigue.
2- Loss strength.
3- Headache.
4- Skin is dry.
5- Constipation.
6- Keto breath.
7- Muscles and joints stiffness.
8- Keto rash.

[johnf]

Thomas can you do a video explaining the difference between Collagen and Collagen Peptides and advantages of one over the other if any? Thanks!

I just love listening to Thomas so much, because of the attention to detail. You hear some doctors say, this & that happens and we don't know the reason why. You here it from them all the time, never from Thomas.

[mariedean]

i tried keto diet mostly because i want to lose weight, i just want o share my experience with it, its really actually hard to sustain plus i do experience very excruciating headache thats why i stopped it and started agoge diet. i di lose weight without all those bad things and i have never been happier

[lorriehernandez]

Can you please tell us what to do about hot flashes young and old people seem to be having them. I have several a day.

[Befri]

When you say that we lose the feeling of strength for a short term amount of time, how short term is this? I’ve been on keto for a month and a half and I still feel weaker in the gym. It’s honestly one of the side effects that’s making me consider giving keto up, but I love the benefits of losing weight, so I feel extremely conflicted