John Ioannidis - Why most clinical research is not useful

[yannis]

Prof. John Ioannidis is probably the most capable doctor in the world nowadays, also extremely good in Mathematics&Statistics and absolutely integer and human. We need people like him urgently. Thank you Professor!

[jukee]

When the worldwide event began in late 2019/early 2020 I looked for this man's opinion immediately. I am an average guy, no degree on the wall and in 2021 many may call me a bum. Call me what you will but I am without any debt, no children by choice as I was aware of the world not being a place in my opinion to raise a child. I am one that surround myself with my books of old and I am selective when reading anything new. Corruption in medicine due to greed is disgusting. I was studying to be a biomedical engineer and walked out as in 2000 the writing was on the wall that money was the most important aspect for those in that career so I couldn't do it and would not throw my soul out for a couple hundred grand a year. This man is a true doctor and a good man. No one is perfect and that is why evidence based medicine is the topic at hand right here. His videos from early 2020 regarding covid were buried and shadow banned. Why? He is not a sell out like most in medicine. Pay attention and you will learn from a wonderful human being. Thank You Doctor.

[yeah]

Ioannidis is a brilliant scientist and researcher and a man of integrity who is exposing a lot of coruption in science. Well done !

[hugo_kruger]

Nutrition Epidemiologists were criticized for using models and not testing them properly by Gary Taubes when the low fat high carb diet was exposed as pure BS.

Today we are seeing what happens again when we follow Imperial College’s modellers down the drain.

[drmuhammad]

So true.. actually 90% of socalled "research" is NOT out of necessity but for personal gain, promotion, recognition or monetary compensation by pharmaceuticals.

[JCResDoc]

18:10 Conflict declarations: Are you declaring you are bowing out of this field (& any influence on guidelines youve had should to be removed). Announcing you are "conflicted" doesnt allow judges to rule on their own cases. And science best have an even higher standard.

[foggymedia]

Wonderful how a mainstream prof at Stanford is questioning the whole mainstream paradigm and vested interest culture of mainstream medicine and medical practices. I'm surprised though he hasn't yet got the boot.

[psychnstatstutor]

Such a fantastic talk about why we need to focus on effect sizes, not NHST

[JCResDoc]

20:30 Therenos - all old is new again (Thanatos)

[JCResDoc]

then they will rush to replicate to not have to think for themselves. all gr8 ideas

[romanszefler]

How do we chenge that hmmm... ?
Just one qestion who pays for any research and what do they expect of it? Always follow the money and eager to control

[RefugeeOfModernity]

he doesn't even mention that he was the first person to call out Theranos. what a great, humble man

[donaldsmith]

In Engineering, we have to consider a factor clearly missing from Professor Ioannidis' claim of overreach in the reaction to the Coronavirus pandemic, which is the "significance of failure." I applaud your contributions to society, I deplore your dissemination of erroneous accusations of overreach, which I also question as a politicization of a tremendously horrific occurrence in the already limited existence of mankind.

[JCResDoc]

15:40 useful & safe - dangerous & harmful on reanalysis

[peterdowney]

How many had data available? 0. How many had a protocol available? 1. Let's be optimistic, that's 100% - don't knock it!

[laurachristensen]

Interesting listening to this now, in light of the COVID situation, where a participant in the back ground is sneezing over and over and

[kcreagan]

Finally, now in 11/2022 the CEO of Theranos, EH, is going to prison for 11 years. Finally, some justice altho it should probably be 30 years.

[naseralriyami]

Discovery is a nuisance

96% of clinical papers since 1990 documented “significant” p-values and claimed to discover something new...

Most “discoveries” don’t end up with any new “solutions” to help change clinical outcomes

There’s a difference between what is “statistically significant” and what is “clinically significant” but we don’t have a standard way to differentiate the two yet...

[romanszefler]

It's so disgrace that most of clinical MD stop having Curiusoty

[anonaki-mtxb]

The Lancet ranked themselves squarely within the ranks of the National Enquirer since the great Covid Plandemic. See Event 201...