Age like Wolverine? David Sinclair Highlights Economic Benefits of Longevity Science

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Dr. David Sinclair and two prominent economists, Andrew J. Scott of the London Business School and Martin Ellison of the University of Oxford, have released a paper arguing that slowing aging can bring gargantuan economic benefits – an order of magnitude bigger than previously thought. The paper was published in Nature Aging and uses a powerful economic model to investigate the financial aspects of increased longevity. The paper is built around a model known as the Value of Statistical Life (VSL). While this question had been raised before by the proponents of the Longevity Dividend, or LD theory, such as Jay Olshansky, the new paper employs a different methodology and arrives at different results, albeit reinforcing LD’s point. The authors offer four scenarios corresponding to four different hypothetical ways in which life expectancy can be increased, cleverly naming the scenarios after famous fictional characters. The first one is named after Struldbruggs, one of the many strange peoples Jonathan Swift’s Gulliver encounters during his travels. The name Struldbrugg is given to those humans in the nation of Luggnagg who are born seemingly normal but are in fact immortal. Just one minor detail though, Struldbruggs have discovered the secret of eternal life but not of eternal youth or health. Therefore, Struldbruggs’ health diminishes indefinitely as they age, making them miserable and longing for death. This first scenario is about extending the human maximal lifespan without a similar effect on healthspan. The authors then analyze the economic value of this particular type of life extension according to VSL. The second is the “Dorian Grey scenario”, named after Oscar Wilde’s character who retained good health and youthful looks until his timely death. This scenario corresponds to increasing healthspan without noticeably affecting lifespan. The third scenario is named after Peter Pan – a character who ages, albeit very slowly. In this scenario, both health span and lifespan are increased, which corresponds to slowing aging. This scenario is the preferred one in terms of VSL and is precisely what geroscience is all about. The fourth scenario, called Wolverine - named after the X-Men character - imagines treatments that reverse aging. Some novel approaches currently in development such as parabiosis, senolytics, thymic rejuvenation, stem cells, exosomes, gene therapy, and cellular reprogramming aim specifically at repairing the damages of aging. The authors apply their model to an actual intervention that most probably works according to the Peter Pan scenario: metformin. According to the paper, if metformin, a cheap, safe, and readily available drug, lives up to current estimates, its use as an anti-aging drug can bring enormous economic benefits. The authors have calculated that just one year of average lifespan extension done by the “Peter Pan way” – i.e., by slowing aging – will bring the US economy a benefit of 38 trillion US dollars, and a 10-year gain would be a staggering 370 trillion US dollars. This is an order of magnitude larger than the previous estimates done by LD theorists.

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#davidsinclair #longevityeconomy #Antiaging #lifespan
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So what are the benefits of longevity for the economy?

LifespanNews
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It should be obvious now to everyone that solving the human aging problem is the most important problem to solve for humanity and will also be the most rewarding in many ways!

hyperkeimeno
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Wow! Unbelievable! Let's all work together to cure aging ASAP!

AiternusCorp
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One more reason I love David Sinclair, Brent Nally and Lifespan News!

SolvingAging
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Curing aging would be the biggest dividend in history!

nozhki-busha
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This is fucking fantastic news! Let’s share this video everywhere!

CryptoLuver
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This video should wake people up! Well done!

George.Gabriel
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Unbelievable! Share this video with everyone!

Ingrid.Barker
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This is my favorite channel because of videos like this!

latinlovur
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So why do you think more people don’t know about or care about solving the human aging problem or the enormous economic benefits of slowing, stopping or reversing human aging?

BrentNally
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Here is the UK, the NHS has been struggling with funding as well as increased demand. On average, people visit hospital more in the last year of their life than the rest of their life combined. If we can increase healthspan, and make it so that last year never happens, the burden on the NHS will be halved. At the risk of sounding cliche, we can afford not to do this.

Do you think its a good idea to contact my local MP, citing this paper? Or would that do more harm than good?

Azmarith
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I've actually never read Gulliver's Travels or The Picture of Dorian Gray. Adding them to my list! Though, those definitely aren't the best options! I'll take Wolverine.

RyanOShea
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In my lifetime, I could be biologically 20 again.

I-Dophler
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I've been retired for 10 years. Started taking Sinclair's regimen and opened a new company within a month. This stuff is the shizznit!@

shedtime_au
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How much would it improve our economy if we solve cat aging?

SallyEndinberg
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Curing aging would also pretty much make COVID obsolete as a deadly disease

JasmineSabine
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The only ethical way forward is to bring an end to aging. Too many people are suffering from heart disease, diabetes, Alzheimer’s, cancer and many other age-associated diseases, not to mention a decline of strength, energy, stamina and robustness. This has got to end! The fact that our elders can be a productive part of society and not a “burden”, contributing to GDP rather than draining it is just icing on the cake.

Let us set our sites high and spend every moment fighting for the Wolverine scenario! Peter Pan should only be the consolation prize if we are unable to achieve Wolverine.

neilchristensen
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The saiyans already slowed down aging considerably we must take

IkeReviews
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I think the next Google, Amazon or Apple is going to be a company that deals with longevity. I mean personally I am willing to go into crippling debt to buy a cure that would give me more time and youth...

jandersen