Top 30 Memorable The Big Bang Theory Guest Stars

Man, nerds get all the best guests! Welcome to MsMojo, and today we’re counting down our picks for the guest stars and celebrity cameos that made the biggest bang on “The Big Bang Theory”. Our countdown includes cameos by Adam West, Katee Sackhoff, Mark Hamill and more! Do you have a favorite “Big Bang” cameo? Let us know in the comments.

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MsMojo is a leading producer of reference online video content of Top 10 Lists, Origins, Biographies, Commentary and more on Pop Culture, Celebrity, Movies, Music, TV, Film, Video Games, Politics, News, Comics, Superheroes. Your trusted authority on ranking Pop Culture.

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[RayBaird-syok]

Buzz Aldrin wasn't the only astronaut on the show. Remember Michael Massimino? He was hilarious!

[jakerocinante]

I love the George Takai appearance, his delivery was great and added to the humor

[JuJuBeeJulez]

“Don’t make me climb over this counter” Octavia was not about to play with him 😂

[dominiquejeannin]

The Bob Newhart episodes were pure gold, he should be closer to number 1.

[joermnyc]

Teller as Amy’s dad was also hilarious. And yes he can talk!

[frankbrodie]

"Live long and suck it!" is the greatest line in TTBT for me. And I love pretty much everything about the show.

[sockygaldamez]

All of these celebrity cameos were awesome❤️ my personal favourites were Mark Hamill James Earl Jones, Carrie Fisher and Stan Lee and Will Wheaton 😄

[queasylagumo]

Good point at the end. Why wasn't Keith Carradine or even Katey Sagal mentioned?

[marcelsgroot]

Still love that line: how about a picture with a guy that looks like nathan fillion but a little more anoyed then nathan fillion usually is

[herdzskyj]

My favourite was Kathy Bates as Amy's mom and Christine Baranski as Leonard's mom.

[luedanger]

My favorite "cameo" is Penny's mom who is played by actress Katey Sagal. I absolutely love Katey. She's been in a bunch of my favorite sitcoms and series

[miguelsilva]

I actually thought that Wil Wheaton and Bob Newhart should have been top 5 since they made the most cameos and the most memorable.

[nicolepowell]

Glad you told me who Rick Fox was. My favourites were James Earl Jones and Carrie Fisher bloody hilarious

[chelseacanales]

I still laugh when Sheldon made a mistake and fainted in front of Stephen Hawking

[joshuampinganjira]

Regina King should be on this list. She was great as Human resources manager at the University

[stephendaurie]

Although not mentioned and only making one brief appearance, Howie Mandel was one of my favorites

[bartoszdulas]

Network: How many Star Trek legends cameos do you want in the show?
Chuck Lorre: Yes

[lacrartezorok]

How can you convince someone to go with you to the Nobel Prize ceremony?
I think "would you like to go to the Nobel Prize ceremony?" may work.

[COMPFUNK]

Elon Musk is a humble person? Is there a second Elon Musk I don’t know about?

[markwallerich]

What about George Smots and Lewis Black?