Adenine Base Editors | ABEs | How Base Editing Works |

CRISPR-Cas9 genome editing has low efficiency and DSB can result in unwanted indels within a target DNA which can be problematic

To overcome this issue, CRISPR-Cas-based genome editing tools...that is base editors have been developed

There are two types of DNA base editors: Cytosine Base Editor (CBE) and Adenine Base Editor (ABE)

Adenine Base Editor (ABE) coverts Adenosine (A) to Inosine (I) within target DNA.