TGFβ Activation and Inhibition | Science Animation

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Peptide growth factors are central to the signalling between and among all cells in the body, and aberrations in such signalling underlie many disease processes. Traditional approaches treat growth factors much like circulating cytokines— to be inhibited systemically for therapeutic outcomes. However, many peptide growth factors are expressed by cells in latent forms that must first be activated in order to carry out their normal functions in a highly localized tissue microenvironment.

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00:00 TGF-β Activation
01:20 TGF-β Inhibition

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#biology #medical #microbiology

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What are the kinds of tgf beta1 inhibitors? What are the bests??

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