Discovery of Melanopsin in Humans

💡Discovery of Melanopsin in Humans: When melanopsin, a light-sensitive protein, was found in the human genome, Panda and his team had a hunch that it played a role in regulating circadian rhythms in humans and mice. Their 2001 melanopsin knockout mouse experiment 🐭 confirmed this link, making it a major breakthrough.

While it was previously thought that the brain's clock was solely responsible for circadian rhythms, Panda's research on mice revealed that peripheral organs like the liver respond more strongly to food cues than light-dark cycles. Food turned out to be more powerful than light in influencing these peripheral clocks.

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