mRNA Manufacturing

mRNA Manufacturing - Anton McCaffrey

Education Session from the American Society of Gene & Cell Therapy's 22nd Annual Meeting

[barbarab]

So how do researchers develop these mRNA vaccines? Is the mRNA visible under electron or atomic microscopes? How do you work / replace messenger pieces at this minute scale?

[Tofu.]

What is the source material for the mRNA? What is it made of and where did it come from? Is it from an animal and if so which one?

[lidarman]

Wow this was uploaded a month before this technology would be needed writ large.

[therealrockguy]

I've never felt so ignorant after watching something. I have a lot of reading to do. I wanted to know the process of making mrna from start to finish. I need to know a lot more before I get to this point.
Can you suggest any videos or books to start with? Thanks.

[vilJOHN]

Ps the catalyst is Gold, you need a lot of it after retiring from being a donor. I found a lot of Gold. The stoichiometry for gold extraction is ore specific and you have to make a formula to get it each time. It's amazing seeing what you can do with stoichiometry and the chemists values getting it balanced the right way. In wet chemistry I can get several ounces waking something up that's never been awake before. The telluride is totally Nuclear Dude!

[TheEmptyeye]

4/22/21 from cdc website..
“ Over 211 million doses of COVID-19 vaccines were administered in the United States from December 14, 2020, through April 19, 2021. During this time, VAERS received 3, 486 reports of death (0.0016%) among people who received a COVID-19 vaccine.”

[cynthiagonzalez]

You don't work these molecules by sight. You know it's working based on indicators/labels.

[tomlee]

The immune system is so incredibly complex, it's amazing!

[darlas]

Maybe I missed it but where do they get the rna to start with? Do they make it in the lab? What is it made of?

[pkpledn]

How long does it take to manufacture and distribute?

[shiyaoli]

Where can I find the presetation slides? In the video the speaker mentioned the slides are on the website..which website?

[vilJOHN]

I know it's perfect timing but it was 30 years in planning. The cryo storage expires after 30 years, and the product is recommended to be used in 10 years. There were millions of quarts in storage and we had to prevent billions of dollars in collections wasted. The reserves are extremely important to our covenants nation security. And to recognize the donors have a life span donating. I maxed out donating at 450 liters and my immune wouldn't support being a donor, causing seizures, having died and cpac back to life. I didn't feel a thing dying, I woke up not breathing, the emergency injected me with lorazepam after a quick lab test to make sure the beta wouldn't cross react.

After that a Donor is done. When you can collect, how many volunteers, will they return. The saline used to not taste like petroleum before the shortage. The needles used to not have nickle "ultra pure stainless only". If you can get it right, maybe you get those donors to return once like me.

Main thing don't waste the stock. PS those vaccines feel like taking ectasy!

[jeriahlee]

Sorry I still do not know how you develop mRNA. Do you use chemical or take a cell from somewhere or from someone ? Please start from the beginning eg like baking a cake, flour, sugar etc... Do you take anything from a bat?

[arielvalverde]

If another RNA Virus is present at the Moment of vaccination, Could be possible that mRNA insert in Virus modifying it instead of the target cell ?

[mironyul]

Does Mrna vaccine permanently alter the genome in vivo, in the animal receiving the vacine?? Anyone know, which method is used to genetically modify a subject

[chrismunns]

Can I continue my methelene blue after my vaccine? I take for brain fog. Thank you.

[ladyalexander]

Which species Messenger RNA is this from and what’s the danger of sick animals mRNA controlling human cells? Oh yes zoonotic disease & sickness!

[harryfire]

self replicating RNA what will they think of next and this stuff is in my vaccine?

[quelorepario]

1:51 illicit != elicit
c'mon dude...

[Luxcium]

Was this the last time these people were thinking « no one else than us in the world knows that mRNA is a thing »