Adam Joyal: Neural Circuitry of Memory in Transgenic Rat Model (TgF344-AD) for Alzheimer's Disease

[vecernicek]

Hi, question here. At 3:19 you say that this strain expresses genes that produce both amyloidosis and tauopathy. According to Alzforum, this strain expresses the Swedish APP mutation plus the deltaE9 mutation in PSEN1. These are both amyloidosis producing genes, right? How does the tauopathy occur?