An Overview of Haldane Effect

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. Haldane effect is the favoring of carbon dioxide loading or unloading by the change in the pressure of oxygen.
In the lungs, oxygen pressure is high, so it helps unload carbon dioxide to be released.
In the tissues, oxygen pressure is low, which helps the loading of carbon dioxide to be picked up.
It is inverse of Bohr's effect.
Dr. Mobeen Syed discusses the influence of the oxygen pressure changes to help load or unload carbon dioxide.
In the alveolus, oxygen pressure is very high(100 mm Hg), which causes the loading of oxygen on the hemoglobin. There is a conformational change in the hemoglobin. It becomes acidic and releases hydrogen. Due to reduced acidity, it favors the release of carbon dioxide. It is the Haldane effect.

The following topics have discussed in the full video:
* Definition of Haldane effect
* Partial pressure of oxygen
* Partial pressure of carbon dioxide
* Mechanism of Haldane effect
* Importance of Haldane effect ...

Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional. ...
Disclaimer:
This video is not intended to provide assessment, diagnosis, treatment, or medical advice; it also does not constitute provision of healthcare services. The content provided in this video is for informational and educational purposes only.
Please consult with a physician or healthcare professional regarding any medical or mental health related diagnosis or treatment. No information in this video should ever be considered as a substitute for advice from a healthcare professional.

[itmarcel]

Thank you, I was reading wikipedia and papers, and I just couldn't grasp it. Your visualization made it much better!

[ibnjameel]

How can I appreciate you
No words for this brilliant mind ❤❤..

[MrKingjames]

But the Bohr effect is decrease in affinity to oxygen by Haemoglobin, so it wont be the reverse of the Haldane effect as you have mentioned

[traceyevans]

So increased O2=increased H+=CO2 offloading and production of H2O+CO2