Webinar: Detection of Medulloblastoma-Associated DNA Methylation Patterns

Webinar on the Rapid and Reliable Detection of Medulloblastoma-Associated DNA Methylation Patterns: MS-MIMIC, presented by Ed Schwalbe, PhD, Northumbria University, Newcastle upon Tyne, UK. The webinar was held on on April 25, 2018.

Detection of disease-associated variations in DNA methylation profiles holds significant potential for diagnostic and research applications. Analysis can however be problematic, samples are often sparse and degraded, making analysis using platforms such as microarrays challenging. This frequently compromises generation of valuable information. To overcome this, we have developed ‘MS-MIMIC’ to identify then reliably analyse DNA methylation signatures with robust clinically-applicable assays. The technique has now been successfully applied to molecular subgrouping of paediatric medulloblastoma cases.