Drusenoid Pigment Epithelial Detachment.

🔷Drusenoid Pigment Epithelial Detachment🔷
🔶OCT Case Series🔶

🟢 Drusenoid pigment epithelial detachment (PED) is part of the clinical spectrum of age related macular degeneration described by Casswell in 1985.
🟢 It is formed by the confluence of large areas of soft drusen and is usually located in the central macula.
🟢 It may be a marker of a diffuse disturbance at the level of the retinal pigment epithelium (RPE) in relation to age related macular degeneration.
🟢 Two hypothetic mechanisms might explain the progressive enlargement.
👉 Firstly, the conflence of soft drusen might be associated with an accumulation of membranous debris external to the retinal pigment epithelial basement membrane.
👉 Secondly, the lipid nature of this membranous debris creates a hydrophobic barrier in Bruch’s membrane, resulting in the accumulation of fluid and enlargement of the detachment.
🟢 Different types of PED have been identified in the literature.
🟢 Drusenoid PED was clearly distinguished from the other types by its better prognosis.
🟢 Formation and persistence of the drusenoid PED, in elderly patients harbouring soft drusen, probably corresponds with the evolution of a distinct subgroup of age related macular degeneration.
🟢 This avascular PED typically develops slowly and causes minimal complaints of blurred vision.
🟢 The natural history reported in the literature has been progression to persistent drusenoid RPE detachment, geographic atrophy, and neovascularisation.

👤 J.R. Fontenla, MD-PhD.
🏨 Hospital Clinic of Barcelona
🏛 University of Barcelona

📚Text-Reference:
👤 W Roquet, F Roudot-Thoraval, G Coscas, and G Soubrane.
📖 Clinical features of drusenoid pigment epithelial detachment in age related macular degeneration.
👉 Br J Ophthalmol. 2004 May; 88(5): 638–642.

I hope you find this video helpful. If you do, please like and subscribe for more videos like this one!

**MEDICAL LEGAL DISCLAIMER**: Visus Formación en Oftalmología does not provide medical advice, and the information available on this channel does not offer a diagnosis or advice regarding treatment. Information presented in these lessons is for educational purposes ONLY, and information presented here is not to be used as an alternative to a healthcare professional’s diagnosis and treatment of any person/animal. Only a physician or other licensed healthcare professional are able to determine the requirement for medical assistance to be given to a patient. Please seek the advice of your physician or other licensed healthcare provider if you have any questions regarding a medical condition.

*IMAGE DISCLAIMER: The content (ex. images) used in this lesson are used in accordance with Fair Use laws and are intended for educational/teaching purposes only*

🟢 Check out some of our other lessons:

Channel Home Page

English Content Playlist

Retina Playlist

Vitreous Playlist

Neuro-Ophthalmology Playlist

Glaucoma Playlist

Cornea Playlist

Conjunctiva Playlist

Uvea Playlist

Lens Playlist

Sclera Playlist

Eyelids Playlist

🟢 Being a Channel Member makes you our Partner. A Partner that contributes to the maintenance of the channel and the creation of new educational/teaching content.
🟢 Being a Member 😎 also gives you exclusive access to:
👉 Videos with additional content.
👉 Multiple Answer Question Bank.
👉 Diagnostic Photo Bank and Photos of clinical cases.
🤩 If you want to become our Partner and contribute to the Content Creation and Maintenance of the Channel, become a member.
Thank you!! 😀👍.