Use of Echo Acoustic Liquid Handling in Functional Genomic Screening of Retinal Ganglion Cells

Presented By: Derek Welsbie, M.D., Ph.D. & Iain Russell, Ph.D.

Speaker Biography:
Dr. Welsbie is an Assistant Professor of Ophthalmology at the Shiley Eye Institute, his laboratory studies the way in which glaucoma leads to optic nerve injury, neurodegeneration and, ultimately, vision loss. His ultimate goal is to develop new small molecule- and CRISPR-based neuroprotective strategies to inhibit deleterious gene function, prevent nerve cell death and improve outcomes for patients with glaucoma.

Dr. Russell has over 16 years of experience in the Life Sciences industry and the genomics field. Iain joined Labcyte and currently manages the Echo® Liquid Handler product line, a series of instruments that enables the non-contact transfer of nanoliter liquid volumes with extreme accuracy and precision. Prior to joining Labcyte, Iain managed a broad variety of novel technologies including microarray and qPCR related instruments and associated consumables.

Webinar: Use of Echo Acoustic Liquid Handling in Functional Genomic Screening of Retinal Ganglion Cells.

Webinar Abstract: Retinal ganglion cells (RGCs) are projection neurons that process and transmit visual information from the retina to the brain. In a group of diseases called optic neuropathies, these cells degenerate, leading to permanent vision loss. We have been interested in using primary mouse RGCs and human induced pluripotent stem cell (iPSC)-derived RGCs to perform functional genomic screens using chemical, siRNA and, most recently, gRNA libraries...

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