Mitochondrial diseases

Mitochondrial diseases are a group of disorders caused by genetic mutations. In this animation, Nature Video finds out how these diseases arise, and how new techniques can stop them being passed on from mother to child.

[croogytude]

Found this via The Lily Foundation. Thank you.
It will help put into words what I find I struggle with when I talk about my child who suffers with a mitochondrial disorder.

[GabrielKnightz]

Please consider making a video on Hemophilia.

A tip to infographic video makers, when you use big jargon words please write it down for those who might want to research it further.

[iamdmc]

some of the best science reporting I have ever seen
thanks

[matthewswartz]

Learned 2 things from this
1. we get our mitchondria from our mothers
2. we can have 3 parents!

[BunmiOwolabiIs_a_Bunmi]

The illustration is this video is compelling and easily comprehensible. Just an error I noticed, mtDNA codes for 13 subunits of the electron transport chain and oxidative phosphorylation while the nDNA codes for almost 1500 of the other mitochondrial proteins (other subunits of ETC and OP included)

[Leen-ihql]

Thank you. Soo much,
Could you please give an example of a
maternal inheritance and a multifactorial inheritance trait or disease in cats?

[uselessstuff]

my little brother has this disses so i was just trying to learn more about this

[TheMarusero]

I saw a study that said that mitochondrias can also be herited from the father but in much more rare cases

[samcoffey]

Cells cells they're made of organelles, try to pull a fast one the cytoplasm gels, the nucleus takes over controlling everything, the party don't stop until the membrane blocks the scene

[RD]

I can't thank you enough for this explanation

[madeleinelatour]

although most of this video is spot on, the information about the coding origin for mitochondrial proteins is absolutely INCORRECT. You said the NUCLEUS only codes for 13 proteins that function in mitochondrial function. YOU'VE GOT IT BACKWARDS! the mitochondrial DNA codes for 13 proteins in mitochondrial function while the NUCLEUS codes for the rest. PEOPLE DO YOUR RESEARCH!

[drivenbycuriosity]

In Jesse's voice.. 'yeah, science!'

[brucepayne]

the cell can produce energy without the mitochondria they will do anaerobic respiration but that person will have a lot of cramps because of fermentation.

[kotosqoposrly]

Why could it be controversial to want a healthy offspring?

[dubayguru]

Thanks I will be using this in a Ted Ed Lesson soon

[koukouvania]

are you pronouncing the name Leigh as 'lay' advisedly?

[mikaelfalk]

'It may be a controversial approach...' well if you keep telling people that it is 'controverisal' then they might feel that way, but there is no reason to take these silly people seriously. At some point you just gotta ignore the anti-science people who oppose everything from stem cells to vaccines to mitochondrial donations to GMO etc.

[SanalMG]

Wont embryo screening a better approach than a tri-parent baby (because all maternal mitochondria are not defective)? Another approach is to take advantage of mitochondria in sperms.

[GalexZ-]

This only says was can be done for what hasn't happened yet. What about the millions who suffer now, what can they do to reverse it?

[brucepayne]

how do you think prokaryotic cells have energy they don't have mitochondria that will need a lot of gluose aka a type of sugar because the form produce energy want more info do some research