How Does Furosemide Work? Understanding Loop Diuretics

The video contains a simple and visual explanation of how furosemide and bumetanide, loop diuretics, work to encourage the kidneys to excrete more water and sodium. We cover some basics about how the nephron works and look in detail at the action of loop diuretics on the sodium-potassium-chloride co-transporter on the ascending loop of the loop of Henle. We also talk about the indications, some practical tips on using loop diuretics, adverse effects and contraindications.

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DISCLAIMER: This video is for education and entertainment only, and is not medical advice. This video should NOT be used for medical advice or to guide clinical practice. The Zero to Finals content should not be used in any way to guide medical decision making. Zero to Finals takes no responsibility for any actions taken or not taken based on the information provided. Local and national guidelines and senior clinicians are there to help you make decisions, not YouTube videos. If you need medical advice or information, seek it from an appropriately trained and licenced doctor or healthcare provider that can address your individual needs. Zero to Finals cannot guarantee the accuracy of information in this video. Please highlight any errors you notice in the comments below - thank you.

[rkaur]

your voice alone is calming and helping me learn.

[shaynecarter-murray]

Every patient put in these meds should be shown a vid like this. It definitely helps to understand the meds and motivate taking them routinely even though the constant bathroom trips are annoying

[AnotherWeirdDay]

Honestly, this was of one the best videos I've ever seen for medical education. Bravo sir!

[blazejp]

I've never seen this concept explained so well. What's missing though is another effect of accumulation of potassium in the cell and its subesquent diffusion into the tubule - this causes positive membrane potential which causes Ca2+ and Mg2+ to be secreted, an important effect of loop diuretics.

[nylonsteel]

Nicely put. One of the simplest explanations of the Loop of Henle I've seen! Really wonderfully done.

[ChroniclesMedicalStudent]

As a 3rd year student I've had many patients taking furosemide and it helped them a lot, but I had not done a more detailed study into it than now. Thanks a lot, this video is very helpful

[dfballa]

Great video! Cleared this concept up just in time for my pharm exam tomorrow :) Cheers from a PA student!

[wadza]

Wow, now that's teaching !!! 👏🏿👏🏿👏🏿. That was clearly explained. You didn't miss a thing. Subscribed and video shared to fellow nursing students. Thank you.

[JamilaS]

Just started my furosemide today. This video = very helpful.

[renzybabe]

This is by far the most helpful video I have watched in all of medical school. There are so many videos available but only this one broke down the small details that make it confusing. Thank you a million times.

[libbye]

This video was insanely helpful. Thank you. You have a way of being crisp and clear with how you communicate topics. Much appreciated! :)

[hj]

Thank you SO much <3 I love your videos short, easy to understand, covering the material in an easy way, good voice, not loud or fast, no music your channel is my Favourite. THANK YOU FOR MAKING THE TIME TO SHARE YOUR KNOWLEDGE

[Bunicutaintelectuala]

Best, clearest explanation I've encountered so far. Great job.

[dak]

Great Teacher! Thanks for Teaching! I leaned this in school about 30 years ago.
Am highly impressed about your clear explanation about " Function of the Kidney" .Thank you!!!

[suepoch]

TFS! My mom is on this medication and my sister keeps wanting to take her off of it but she swells so bad in her legs. Great video and directly to the point!👍👍👍👍👍✌️❤️🇺🇸🇺🇸🇺🇸

[itsJaysPOV]

I appreciate the pace and conciseness. Thank you!

[medicoinprogress]

I had a test yesterday at 9 am. I watched this video at 7 am. There was a question on Furosemides and I could answer this question pretty well thanks to this wonderful 😊😊

[allenroyal]

nice one mate, simple and easy and you covered background info... keep it up pal

[bn]

Thank you this was very well explained. I have a lot of issues learning about loop diuretics and countercurrent multiplier but it is so clear to me now.

[aakrutimore]

This helped me so much!!! Much more strength, knowledge and good luck to youuu!!!❤️