Lineweaver Burk plot

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A typical curve of enzyme kinetics is a plot of a plot of velocity of reaction vs substrate concentration. As the substrate concentration increases the velocity of the reaction increases until it reaches a plateau, which is known as maximum reaction velocity or Vmax. The drawback of this graph is that the plateau region is not perfectly horizontal. Beacuse of this there is a error in the estimation of Vmax and Km. Hence the researchers started modifying the graphs to get better estimate of Vmax and Km. One of such graph is lineweaver burk plot.
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I remember watching this in university and I never forgot how helpful it was. Now 4 years later, I'm coming back to it in medical school <3

rachael
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*watching video after getting all lineweaver burke questions wrong*
"hence, lineweaver burke plot is one of the easiest graphs to understand enzyme inhibition"

Woogie
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I was procrastinating because this seemed really hard to understand. Thank you!

specilist
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This is perfect to understand whatever the hell is this lineweaver burk just wow

theinkedaaila
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Yoh!! im writting tomorrow and i thought i was gonna fail this burk plot and now i get it. Thank you!!!!

bobmogoboya
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Thank you so much for making it that simple for understanding in a better way

surbhisharma
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Sometimes the easiest math seem difficult @ 2 o clock at night. Thanks for making it clear!

gayatri
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THIS video makes it all clear! THANK YOU!

katejbradshaw
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You are probably going save my exams today

MzPeregrine
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Thanks, this made it so much easier to understand

stellawanjiku
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I thought it's very hard
But seeing this video clear all the doubts thank you ❤️

jyotsnaraut
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Quick and excellent explanation. Thank you!

nicolevillalon
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Awesome explanation. Thank you veeeery much 🙏🏿

nyikomhlarhimusic
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Thank you! the mathematics explanation helped explained how Vmax and Km value changes can be infered from the Line - weever. I guess thats the point of it, make it simple to see changes.

Drift
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I thought this was hard u made it so easy thank u

Kingmi
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I dont understand how you get the -1/km as the x intercept

alyssatipler
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the only video that i understood thanks alot 😭🙏

mayryelll
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What values on the plot are Vmax and what value is Km?

kamariweaver
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thank you so much i was so confused what was difference between the michaelis-Menten vs Lineweaver-Burk chart was

apollomarley
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thank u alot :) really helped me for my assignment :)

logitfau