Griffith's Experiment/Bacterial Transformation (Griffith's Experiment)

Have you ever wondered what determines your height, hair and skin color and even the size of your nose?

It’s DNA, the genetic material of cell. But do you know how it has been proved?

Here are the experiments that proved it.

Griffith’s Experiment:

Griffith took two strains of pneumococcus bacteria.

1. S (III) – which have smooth polysaccharide capsule, giving smooth colonies (S) and is virulent causing pneumonia.

AND

2. R (II) – which have no capsule, giving Rough colonies (R) and is avirulent unable to cause pneumonia.

When the virulent S (III) bacteria injected in mice, it killed them causing pneumonia.

But when the Avirulent R (II) injected in mice, the mice lives

If you inject the heat killed virulent S (III) bacteria, the mice still live. Implying that live S (III) bacteria are needed for causing pneumonia

But interestingly, when mice were injected with the mixture of heat killed virulent S (III) bacteria and avirulent R (II) bacteria, mice died.

Analysis of dead mice reveals live S (III) virulent bacteria suggesting something form the heat killed S (III) had transformed to the live avirulent R (II) bacteria, responsible for the transformation of the live avirulent bacteria to virulent S (III) bacteria, causing death of mice. This is called as Bacterial Transformation.

To prove DNA is genetic material, team of Avery et al and Hershey and chase performed another experiments. See other video for it.

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[KuteKarisma]

An hour and a half lecture explained ing less than 2 mins, awesome !

[Cerebrozedutree]

@Raisa Ilyas: We are Glad you like it, Do subscribe to the channel for other great videos.

[vkhateworld]

Great and easy way of learning the concept of Bacterial transformation. loved the way you guys have made the video. look forward to see more video from you guys.

[anonymousswagger]

This is Awesome! I aced the test because of this video! Thank you very much!

[Cerebrozedutree]

Hi Aimee, other video will be uploaded soon. Thanks for your comment and apologies for inconvenience. Do subscribe so you will get notified once we Upload the new videos

[Cerebrozedutree]

+Raisa Ilyas: Do share it on FB and spread the word to your friends and help them learn easily.

[ilovefredreika]

Images help a lot in making clear. Thank you.

[satya]

At starting both colonies developed from two different bacteria Or one bacteria plzz explain.

[vijaykumarkantharia]

Great Video, Explained it nicely. Loved it, look forward for more videos.

[jaiminsadhu]

Oosum video easily understand.
Sooo good

[timdunkelberg]

Very well explained, though I found it quite hard to focus well with the music in the background. Would prefere the video to be without music.

[ChiragKSnet]

Loved Your Explanation :) Simple and Neat !!

[sherrwagn]

Why don't you have more views? These are really great

[lorenasantamaria]

The next video from Avery et al. experiment?

[vikastiwari]

Very greatly explain the concept about Griffith experiment

[armindedic]

Why is this the only video on your channel ?.
You're videos are great. Good explanation.

[mountain]

Can you please tell me what software you use for the animations? I really like them. Thanks

[enochkayHQ]

Very interesting. Can't wait to have the rest of the videos.

[TheLegend_Infotainment]

really interesting video ireally like this

[BAl-mftl]

i love this video this is explained so easy