190: Resiliency Radio with Dr. Jill: Manifestations of Mast Cell Activation (MCAS) in the Gut!

In today's episode, we interview Dr. Leonhard Weinstock on the topic of mast cell activation disorders and the gut, which are becoming epidemic in the population.

Mast Cell Activation Syndrome (MCAS) is a complex and often misunderstood disorder that involves the abnormal release of mast cells in the body. These cells are an essential part of our immune system, but when they become overactive, they can trigger a range of symptoms and health issues.

Key Points
✅ How did you get into the study of medicine and gastroenterology and what led you to become an expert in MCAS?
✅ Describe in detail what symptoms are related to MCAS and how symptoms might manifest in the gut and other areas of the body?
✅ What do you think we've seen a rise in MCAS diagnoses?
✅ Let's talk more about TRIAD (EDS, MCAS, POTS) and how this can manifest together?
✅ What are some ways we can treat MCAS?
✅ What is the connection with MCAS and psychiatric symptoms/mental illness?

Dr. Leonard B. Weinstock
Dr. Leonard B. Weinstock is Board Certified in Gastroenterology and Internal Medicine. He is an Associate Professor of Clinical Medicine and Surgery at Washington University School of Medicine. Dr. Weinstock received his medical degree from University of Rochester School of Medicine and completed his postgraduate training and was chief resident in Internal Medicine at Rochester General Hospital. His Gastroenterology Fellowship was performed at Washington University School of Medicine.

Dr. Weinstock is an active lecturer and has published more than 140 articles, abstracts, editorials and book chapters. He has given lectures throughout the world. He is currently researching mast cell activation syndrome, small intestinal bacterial overgrowth, restless legs syndrome, mold toxicity, and rosacea. Fifteen articles related to MCAS have been published within the last 5 years.

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✅ The views and opinions expressed on Dr. Jill LIVE! do not necessarily reflect the official policy or position of the host. Any content provided by guests is their opinion and are not intended to malign any religion, ethnic group, organization, company, or individual nor do they necessarily reflect the views or positions by the host.

[qingdaogrrl]

I'm so lucky that the majority of my psych issues were resolved by moving out of a moldy environment - however - the MCAS symptoms are getting worse / more noticeable as I treat the last bits of ochratoxin left inside me so was very interesting to hear this doctor's research on anti-anxiety meds / treatment of MCAS first and then psych issues resolved for some patients. So incredible all the things that we don't know that we don't know!

[cammandolord]

Can someone lead me to anemia and mast cell?

[michellet]

If someone gets burning throat and abdominal pain, cramping, and anal itching after meals, can this be MCAS? Can gut symptoms after meals be the only presenting symptoms of MCAS, eg. the person doesn't have hives or POTS.

[ScottHammond-vxyl]

I think you are being a harsh. He is bringing the best allopathic science and principles to a condition little understood by physicians and should be applauded for his efforts. A one hour interview can not reveal the scope and understanding of his work. We should be working together sharing opinions and ideas and not bash other honorable professions..

[sankarawasright]

If you are a sick person listening to this you must approach this conversation with a critical lens. This MD is a leading researcher of MCAS and has little idea of what causes it. He runs multiple tests for the presence of mast cell dysfunction but not a single test for the causes of mast cell dysfunction, e.g. mycotoxins, pesticides, heavy metals, etc. He wouldn’t even know how or where to order the appropriate studies, let alone interpret them. An MCAS diagnosis can be made clinically, especially if the only treatment modalities include MC stabilization, the fact that he’s agitating patients in order to confer a positive result is an ode to the sadistic tendencies of Allopathic medicine. If a hypersensitive pt can barely tolerate a whif of Clorox at the supermarket how are they going to tolerate a compounded pharmaceutical like ketofin? The second and third level interventions this MD lays out are a path to polypharmacy, a gj tube and the morgue. Versed? Propofol? Benadryl? Solumedrol in the presence of SIFO? These people want you dead. Complex chronic illness sufferers need to avoid Merchants of Death like this and seek out Environmental Illness specialists who have the tools, technologies, and methodologies to treat the root causes of MCAS and other co-morbidities.