Friedman Brain Institute Research Scholar: Silvia De Rubeis, PhD and Zhuhao Wu, PhD

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Fascitelli Research Scholar Awardees:

Silvia De Rubeis, PhD, Assistant Professor, Psychiatry
Zhuhao Wu, PhD, Assistant Professor, Cell, Developmental & Regenerative Biology

TITLE: Capture the cellular and molecular drivers of cortical development in DDX3X syndrome

ABSTRACT: In a new collaboration, the De Rubeis and Wu labs will study the cellular and circuitry mechanisms underlying DDX3X syndrome, a rare genetic condition associated with intellectual disability and autism spectrum disorder. The researchers will explore how cortical projection neurons develop in a novel mouse model of DDX3X syndrome using a combination of whole-brain tracing of cortical projections, circuit mapping, and molecular profiling. This study aims at opening new horizons for understanding and treating DDX3X syndrome.

Icahn School of Medicine
FBI scholar
Research Scholar
Mount Sinai Scholar
Friedman Brain Institute
department of neuroscience

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