Tumor Suppressor Genes - p53, pten, p21, pRB

This lecture explains about the different types of tumour suppressor genes including p53,p21,p10, pRB and so on. Tumor suppressor genes are constitutively produced in cell that regulates cell cycle stages and make the decision to either fix any DNA damage or to kill the cell with apoptosis pathway. Tumor suppressor genes are normal genes that slow down cell division, repair DNA mistakes, or tell cells when to die (a process known as apoptosis or programmed cell death). When tumor suppressor genes don't work properly, cells can grow out of control, which can lead to cancer.
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