JMBBM Frontiers Webinar - Gianluca Tozzi - December 10, 2020

TITLE: Understanding the mechanics of musculoskeletal tissues and biomaterials using digital volume correlation (DVC)

SPEAKER: Gianluca Tozzi (University of Portsmouth)

MODERATOR: Hanna Isaksson (Lund University)

SUMMARY: Digital volume correlation (DVC) is an imaging-based technique with the unique ability to measure experimental 3D full-field displacement and strain in materials undergoing motion or deformation. In recent years, the technique has been rapidly growing in the evaluation of bone, biomaterials and bone-biomaterial systems using input 3D images mainly from X-ray computed tomography (XCT), achieving increased temporal and spatial resolution (Synchrotron-XCT). This webinar is intended to present our research advancement in the use of XCT-based DVC to unravel bone mechanics from organ to tissue level, as well as its integration with various biomaterials and quality during different in vivo regeneration models. In addition, the use of DVC to measure the full-field strain in osteochondral tissue (including articular cartilage) by exploiting propagation-based phase-contrast imaging will be also discussed. Overall, the findings have the potential to pave new avenues for advanced tissue mechanics and provide the perfect framework to inform predictive computational models; ultimately improving biomaterials design, diagnostic tools and surgical practice.