Alcohol, Hangovers & How to Cure a Hangover Based on Science | Dr. Andrew Huberman

Dr. Andrew Huberman discusses the causes of hangovers and ways to reduce or eliminate hangover symptoms.

Dr. Andrew Huberman is a tenured professor of neurobiology and ophthalmology at Stanford University School of Medicine and host of the Huberman Lab Podcast.

#HubermanLab #Alcohol #Hangover

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The Huberman Lab Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.

[TheBrenaissance]

Anyone else here absolutely fighting for their life right now?

[chrisbaker]

I’m only 32, but my body no longer seems to process alcohol the way it used to. Not only are the hangovers vicious and last up to two days, but the “drunk” feeling in the moment is no longer enjoyable. It used to alleviate my social anxiety, and make me feel happy/excited. Now it just makes me feel sleepy, dizzy, and sick to my stomach. It doesn’t seem to matter if I’m having 1-2 drinks, or 6. I feel sick, sleepy and gross in the moment, and am rendered completely useless the next day with migraines, acid reflux, aches and pains, etc. I’m essentially experiencing all of the side effects of the poison, without any of the benefits. I have stopped drinking completely for this reason, although I do wish I was able to have a couple drinks every now and again without having to feel terrible, and lose an entire day after. Oh well, I guess 🤷🏻‍♀️

[highvalue]

I drink because I get anxiety at work as a bottle service girl and then the next day I wake up with more anxiety. I’m so glad I found this video

[botbadger]

RECAP:
- Restore gut microbiome.
- Safe deliberate cold exposure 1-3 minutes or upto 10 if you can handle it. The temperature should make you want to get out but you know you're safe staying in.
- Drink water or optimally drink electrolytes whilst drinking, or if you don't do that, drinking them before bed and/or when waking will be fine.

[seismixx]

I never understand how people drink to fall asleep. I wake up like every 30 minutes if I drink before sleep.

[TheRooster]

"Hair of the dog" refers to an old supposed treatment for rabies - the hair of the dog that bit them was put in the wound as part of the treatment.

[tylerstrow]

What happens if you just use hair of the dog 7 days a week and avoid the hangover completely, forever? Oh that's right, I'm an alcoholic.

[gritcrit]

One time, I was chugging red bull while drinking to stay awake. The next day I got this huge acute depression. It was worse than any hangover I ever had in my life.

[andreadeans]

If you’re struggling with hangxiety, I recommend listening to some ASMR videos . If you’re new to that it’s a way of calming your mind using sounds and music

[HappyMerchant]

My notes ⭐ So sleep well. Eat probiotic food. Take non-steroid antinflamatory (but take into account the liver issue). Not ingest more alcohol. Cold exposure, cold shower (be careful with hypothermia). 2 glasses of water wity electrolites (salt) for every gkass of alcoholic drink. Anyway, for me a Monster Rehab lemon tea + high fat high protein high sodium fast food like KFC does the job

[skvlsky]

That pseudosleep thing is real man. I'm always getting 7, 5hrs of sleep but last night I slept only 1 hour and I have this hangover like feeling

[candicerick]

The cold exposure is so true! Being from South Africa, our holidays were always in beautiful beach places and nature areas. when I was younger I would go for a night out during the holidays. The next day we would all meet to go to a waterfall, the ocean or some cold water source because the heat of the day and the hangover wouldn’t mix well. After the swim the hangover would be much better. So interesting to hear the science behind it thank you Andrew!

[oliwakulla]

As a regular drinker for over 10 years, I can say this - only cure is a time. Or alprazolam (Xanax) if it's very bad.

[JK-hsii]

I wish you’d mention the alleviating effects of sweating/exercise. Something about sweating out the toxins

[PhilPaoletta]

For the hangxiety, alcohol increases GABA which is like hand brake for neurons. Once that wears off glutamate network goes into overdrive. This increases neural activity, can even cause seizures... This is a big part of the hangxiety

[Grgna]

Having alcohol on hangover does not cause worse hangover. You can have one or two beers during the day and you will feel much better and certainly not be hungover the next day

[PritamBankar]

Anyone here with strong headache after alcohol last night?

[MrJ-bn]

Ahh the good old hangover blues. Or as my friend calls it 'Post binge loser complex'

[raviisjassi]

I had 8 skooners its really stressfull and dizzy pls dont drink more then 4 . Enjoy turns into tension

[Scutty-Snark]

I was under the impression hangovers are at their worst in the morning because the liver has converted the ethanol to oxidative byproducts during the the night, and switches to the methyl/ formyl products by morning. This creates formaldehyde and the majority of the pain (Along with all the other factors).
Having a beer in the morning puts ethanol back into ADH as the preferred substrate (instead of MeOH), so there is some pain relief while ADH churns away on its least preferential substrate in the background.

I can understand if you don't want to get into these details, but this is very old kinetic information.