This could shorten your lifespan | Lifespan News

The GrimAge clock, an accurate predictor of age of death, shows that major depression accelerates aging; the NIH launched a large-scale project to study senescent cells; selenium supplementation seems to protect against obesity in mice; we'll have these and other stories in this episode of Longevity Science News.

CHAPTERS
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0:00 Intro
0:19 GrimAge is accelerated in major depression
1:24 Pace of Aging (“Youthfulness begins in youth”)
3:26 SenNet: The NIH Large-Scale Cellular Senescence Initiative
4:21 Selenium Supplements Protect Against Obesity in Mice
5:09 How brain cells repair their DNA reveals 'hot spots' of aging and disease

SOURCES AND FURTHER READING
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GrimAge is accelerated in major depression:

Pace of Aging (“Youthfulness begins in youth”):

How brain cells repair their DNA reveals 'hot spots' of aging and disease:

FOOTAGE, IMAGES, AND MUSIC CREDITS
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Music: "Retro 80s technology" by Eric Matyas

Other Credits:
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#longevity #aging #epigenetics #senescence #supplements #obesity #brain #dna

[LongevityScienceNews]

If the topic of epigenetic clocks interests you, subscribe! We'll be having episodes about that soon.

[Health.First.]

Depression is even more depressing...it’s important to stay positive! Fantastic video!

[CryptoLuver]

The GrimAge depression correlation isn’t surprising and, in retrospect, is obvious. Nice video!

[neilchristensen]

Great news segment! Thanks!

There were a lot of exciting items in this episode. I am really excited about the continued progress in biological clocks and this new connection with depression. I also think the measurement of the neuronal DNA repair sites is really cool and exciting. My top item, however, was the NIH funding of SenNet with the hope that this does represent the beginning of a paradigm shift at the national level.

[madamwiperfluid]

Where can one have their DNA methylation rate tested?

[undiagnosed]

Fantastic about the NIH getting on board for senescent cell research. They will really change things. Keith and Elena know how much I've been pushing for NIH involvement in aging -- I admit I was a broken record for a while. I don't know what the trigger was, but I am delighted that the biggest biomedical force in the world, with $41 billion+ in its budget, is running with this. When the NIH starts getting results that are pragmatically useful, they will expand into more domains of aging. Now the big issue we face, as I have been saying since 2014, is to get the NIH budget up, with significant allocations to the National Human Genome Research Institute and the National Institute on Aging, in addition to raises across the board into the 25 other institutes at the NIH. This is another issue on which I am a broken record. Hopefully the music this broken record makes resonates with enough people to effect change, because health is most important, and less than 1 cent per tax dollar we pay goes toward curing EVERY disease, including those of aging and aging itself. I think it should be at LEAST 2 cents per tax dollar.

[littlevoice_]

What if someone with depression takes steps to improve their mental health such as medication, exercise and supplements?