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The gating cycle of a cation channel
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McCarthy et al. illustrate in this video the conformational changes that occur in the pore of the P2X7 channel during the gating cycle.
McCarthy, A.E., Yoshioka, C., and Mansoor, S.E. (2019). Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization. Cell. 179.
McCarthy, A.E., Yoshioka, C., and Mansoor, S.E. (2019). Full-Length P2X7 Structures Reveal How Palmitoylation Prevents Channel Desensitization. Cell. 179.