Used Mercedes S-Class W221 Buyers guide (2006-2013) Avoid faults and common problems (CDI/AMG)

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Mercedes S-Class W221 used car buyers guide and owners guide for S280, S300, S320, S350, S400, S450, S500, S550, S600, S63, S65. Should you buy a Mercedes S-Class W221 if you want a reliable luxury Mercedes. Find out about the Mercedes S-Class W221 reliability and the common faults to look for and what to avoid. This guide covers the CDI engines, the gas/petrol engines including V6, V8 and V12 BiTurbo, and as is sometimes separately designated the CGI engines. No matter if you are looking for an SE, Avantgarde, Sport, or AMG model you'll find useful information in our guide.

If you have been thinking about whether you should buy a Mercedes S-Class W221 from 2006 S-Class, 2007 S-Class, 2008 S-Class, 2009 S-Class, 2010 S-Class, 2011 S-Class, 2012 S-Class, and 2013 S-Class or are curious about the facelift engine differences watch through our guide for the information you need. Avoid buying a broken Mercedes S-Class that becomes expensive to repair by finding out the common faults to look out for.

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Creator -

Miles Goodson

Legal and disclaimer - Any content not originally created by The Miles Driven remains the property of the original owner and is editorialised for media reporting. All content is used within the confines of media reporting/editorial use and is transformative in nature to inform others with new information and content about cars and vehicles. We use no more of the original content than necessary in alignment with U.S copyright law for fair use and U.K fair dealing. We accept no liability for the purchase of vehicles using our guide and suggest thorough due diligence by individual professional inspections before making a buying decision.

The Mercedes W212 E-Class was first released in 2009, our buyer's guide helps you to buy and own a Mercedes W212.
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themilesdriven
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I just sold my s class. I miss it allot! Not many people know about this generation as much as I can research. Watching this video I have to say everything here is a fact. Currently looking to get another s class so if anyone has the 6.2 AMG in the UK hit me up!

tanvirhussain
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Great review! I own an S65AMG and an S63AMG V8 BiTurbo Performance pack. The W221 is my fav S class Mercedes that’s why I bought a prefacelift and a facelift model. I also used to own an S600 W221. Out of 3 models, the S65 V12 BiTurbo engine is something special! The V8 BiTurbo is not far from the V12 power wise but no other car sounds as good on start up as the V12 and once you’re doing over 60mph, the V12 is in a different league!

Sam_AMG
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I love my 2009 s550, I bought it with 77, 000 miles and only has 90, 000 now.
I recently purchased 22” brushed face alloy wheels which I can’t wait to install.

theurbanartist
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What a wonderful review of my dream car 😮

theurbanartist
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I really miss my C216 CL500 and W221 S63, after being able to drive almost every possible car, the S-Class is always unmatched

Max-bkhm
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Excellent report but I believe there were issues with the plastic swirl flaps in the induction manifold of my 2006 W221 350V6 petrol. I was told that they can break up and be ingested by the engine and cause major problems

richardjennings
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My 07 S550 is the best daily driver I've ever had.

kevinc
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Some of the l/100 km numbers seem oddly high compared to the MPG numbers.🤔

imnotusingmyrealname
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My S65 is unbelievable. These can be tuned to well over 700 hp. Cold start is...what did the hottie sales girl down at the MB dealer call it?...oh, yeah...a "panty dropper".

seanhoward
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less electronics than W222, should be more reliable, no?

papagen
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Im about to buy a 09s550 130k miles any tips pray for me

slightwork
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Is this really titled: Avoid Common Faults and Problems? How about Chronic faults: "Everything to do with the farcical S400 Hybrid system"!!! Mercedes covered up all Generated/Charging system failures which are a very expensive design failure! I can't believe you didn't mention the S400 and didn't say a single word about the major issues that turned this car into an expensive driveway ornament! Why? Did Mercedes sponsor this video, because I find it hard to understand why you mention everything benign that can go wrong, but ignore something that can cost you $15, 000 to repair, strange really!

spook