Amyotrophic Lateral Sclerosis Treatment Using Acupuncture, Pharmacopuncture and Herbal Medicine

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ALS , often referred to as “ Lou Gehring’s Disease,” is a progressive disorder that causes degeneration of the motor neurons in the spinal cord, brain stem, and motor cortex that control the voluntary muscle movement.
The average ALS patient’s life span is less than three years from when symptoms first appear. Unfortunately ALS is progressive disease until death. The significant symptoms of ALS include muscle spasticity, muscle weakness, paralysis, fasciculation, impaired speaking, swallowing and breathing. Acupuncture treatments showed the high correlation with K-ALSFRS-R score and Sa-am acupuncture lung tonification. And Sa-am acupuncture lung tonification would be more effective on early stage of ALS disease. We found that Pharmacopuncture of Bee venom, Scolopendrid and Hominis Placenta attenuates neuroinflammatory events and extends survival in ALS models. We observed that Mecasin, a novel antineuroinflammatory Agent, inhibits neuroinflammatory responses and Mecasin exerts a neuroprotective effect by ameliorating oxidative stress via heme oxygenase-1 upregulation. According to analysis of clinical trial, the low dose or high dose mecasin group showed better results than the riluteck control group.