Webinar: Enabling Structure-Based Drug Discovery for Membrane Proteins

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In this webinar, Dr Michael Hennig, CEO of LeadXpro talks about LeadXpro's platform to screen, optimize and structurally characterize small molecules and biotherapeutics in complex with drug targets. Showcase examples will include the structure determination of the chemokine receptor CCR2 by X-ray analysis and cryo-EM structures of human TRPV4 with bound small molecule agonist as well as an antibiotics transporter target.

0:00 start
1:26 Introduction Michael Hennig
3:14 Start presentation
3:45 Introduction LeadXpro
7:33 Expression and purification of membrane proteins
13:29 ligand binding
25:42 LeadXpro vision
30:12 LeadXpro Success case
36:54 Key benefits for chemists
40:30 Why work with LeadXpro
42:27 Question 1
43:20 Question 2
45:03 Question 3
47:08 Question 4
49:02 Question 5
52:06 Question 6
54:32 Question 7
56:04 Question 8
56:54 Question 9
58:04 Question 10
59:50 Outro message
  1. Symeres
  2. Cryo-EM
  3. Leadxpro
  4. Michael Hennig
  5. webinar
  6. research
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