Electron Transport Chain (Oxidative Phosphorylation) | Metabolism

In this lecture, EKG is going to cover oxidative phosphorylation, which includes the electron transport chain and ATP synthesis. EKG will break down how the electron transport chain works, how the electrons are passed through the protein complexes, generating a proton gradient, and how ATP is synthesised. Then, EKG will go over how inhibitors inhibit the different parts of the chain and how this affects oxygen consumption and ATP synthesis.

Table of Contents:
0:00 Intro
0:42 Importance of Oxidative Phosphorylation
1:33 NADH & FADH2 (Important Electron Carriers)
2:43 How The Electron Transport Chain Works
9:20 Proton Gradient (Proton Motive Force)
14:25 Inhibitors
18:05 Complete Oxidation of Glucose

Lecture Source: Nelson, D. L., & Cox, M. (2017). Principles Biochem 7e (International Ed). Macmillan Publishers.

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[sanskritijha]

I missed couple classes due to illness and your videos are helping me out a lot! thxx

[Sam_]

Outstanding presentation. Keep up the amazing work

[rdance]

Excellent Video! Just one question: F0 of ATP Synthase is made up of 12 subunits, while F1 has 6 parts but only 3 moving. It takes 4 protons to make 1 ATP, based on the mechanics of the enzyme. If Complex 1 makes 4 protons from 1 NADH, how do we get 2.5, when conventional wisdom would assume just 1 per molecule of NADH?