Brandl's Basics: Somatic hypermutation and class switch recombination

This video describes two processes that occur during B-cell differentiation in the germinal center: Somatic hypermutation and class switch recombination.

[myspringatgate]

I learned more about VDJ recombination in this 5 minute video than I did in my first 2 years of med school... THANK YOU.

[SubashAdhikaridr]

This is one of the best videos around the topic.

[loveforbioinfo]

Your video is the best! Love the content. Well explained.

[raanoooshh]

Thank you for explaining the difference!🙏

[stichymckelles]

Great explanation 👍🏻👍🏻👍🏻👍🏻 Beats having to go through a million reference books and going to lectures and falling asleep 😴🤣

[TragedyOfDarthPlagueis]

Thank you for this video - very good explanation 😊

[kannukandiddu]

very well explained. Helped a lot, thanks !

[giuliocasalis]

very very well explained, great work. thank u!

[hni]

Thanks so much for making this video!!

[TaiNguyen-twgp]

Very nice and clear explanation! Thank you! (:

[jonahmj]

thank you for this lovely i now understand the two pretty well

[DrSanjayNatarajan]

Amazing lecture. Is Interleukin 5 also involved in promoting IgA production apart from TGF Beta?

[minileadja]

thank you very much for the very clear explanation!

[GeorgeMatthews]

can someone please help. At 4:40 she said "if we were infected with *somthing* in mucosal tissue" what is that something. Basically i want to know when the Tfh would secrete more IL-4 making IgE

[cloudmer]

Thanks a lot, I understood everything!!

[saviourlives]

Excellent explanation mam, Thank you 🙂

[fadeskywards]

Why doesn't the cut-out part just be spliced as an intron in mRNA?