Dr. Aubrey de Grey - Changing Priorities in Rejuvenation Technologies - Lifespan.io

De Grey is the author of The Mitochondrial Free Radical Theory of Aging (1999) and co-author of Ending Aging (2007). He is an international adjunct professor of the Moscow Institute of Physics and Technology, a fellow of the Gerontological Society of America, the American Aging Association, and the Institute for Ethics and Emerging Technologies.

SENS Research Foundation works to develop, promote, and ensure widespread access to therapies that cure and prevent the diseases and disabilities of aging by comprehensively repairing the damage that builds up in our bodies over time.

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It's great to be here, of course. I just thought I'd start by saying that some of you may have heard perhaps of a complication that's going on in my life right now. I just wanted to say that there is an independent investigation, which was started at the beginning of July and is still ongoing. That, of course, means a couple of things.

First of all, it means that I am on administrative leave, which means that I am not representing SENS Research Foundation here today; officially, I am here in a personal capacity. I should mention that I just noticed I have the SENS Research Foundation logo at the bottom of all my slides, so please pretend that that isn't there.

Apart from that, I can't say anything more at all about what's going on; of course, this would be the wrong place anyway. I just want to say how overwhelmed I am for all the love and support that I've received from hundreds and hundreds of people, and it shouldn't be long now. So you know, watch this space. So, having said all that, let me share my screen.

I thought I would talk today about the changing priorities that I see that we have in this field at the moment, because it's very easy to get very optimistic and excited about how things are going. No question, things are moving much faster than they were even a few years ago, but I believe that those of us here who are really at the forefront of this crusade need to be absolutely clear that there is an awful lot still to do.

I thought I would start in illustrating that by using some of the slides that you're very familiar with but with different titles than you may have seen. Of course, you know about this, it's the increase in life expectancy that has happened over the past couple of centuries, and, of course, that's a wonderful thing.

It is the result of progress that we have made initially in the elimination or virtual elimination of infant mortality from things like tuberculosis. And subsequently, as we've gone on, the reduction in mortality rates at older ages, which has been absolutely wonderful. And it has certainly resulted in greater quantity of life and quality of life.

But as we all know, the result is that more and more people are reaching ages at which they suffer from the chronic progressive health problems of late life. As usual, I'm just putting up this slide showing the economic outcome of that, which is completely catastrophic, in terms of the rate at which we are having to increase the proportion of the economy that is allocated to medical care. It's completely terrifying, and something better be done about it.

Of course, that is very much in the minds of people across the board, policymakers, the private sector and so on. But, what to do about it is something that, of course, we have rather less consensus on as things stand. I mentioned all that because it kind of illustrates how priorities change, that when you identify a particular problem or a particular bottleneck, and you make progress on it, other ones pop up in their place.

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#Aging #lifeextension #rejuvenation #biotech #rejuvenationtechnology #longevitytechnology#aging #longevity #EndingAgeRelatedDiseases #LifespanIO #longevitytechnology #EARD

[LifespanIO]

What should be the main priority in rejuvenation?

[falsexgrindx]

Don't let anyone push you around, Aubrey. We all have your back.

[brewhog]

I'm glad to see you're still trucking on and focused on continuing your life's work.

[jeremyburghall]

Really appreciate hearing Aubrey's macro perspective on the situation.

[mistwalker]

There is definitely a shift in discourse around aging and longevity; and Aubrey is right when he is constantly calling to arms. We need to keep pushing!

[tomu]

Glad to see you again Aubrey and really excited to hear some new updates! You were treated really unfairly and it was a disgrace what's been going on. What a sham!

[Gi-Home]

Appreciate Dr. Aubrey de Grey's work and drive to cure the disease of aging, wish Aubrey the best.

[rafaeladrian]

Aubrey please make your own channel with a link tree

[warioland]

Keep pushing forward everyone and don't back down. We can overcome this fight and win it. I know we can.

[nozhki-busha]

It is great news that more people are moving to support doing something about aging but as Aubrey says, there is indeed a lot more to do before that battle is won. Thanks to Aubrey for giving this interesting talk.

[bradhilton]

Thank you Dr de Grey for your herculean efforts in raising public awareness of the possibilities. I hope all goes well for you.

[ambrishjaiswal]

i was so worried about you Aubrey. 😭😭😭

[serenity]

This will just be a minor setback Dr. Aubrey de Grey, I have tremendous respect for your outstanding work.

[LifespanNews]

We just posted a summary of this talk on our channel if anyone is interested!

[nonmagicmike]

I deeply hope you stay the course. A year or two of delays is nothing compared to the potential benefits of such therapies eventually becoming accessible to millions of people.

[ct]

I wonder what he thinks of Altos Labs, which Jeff Bezos and others founded recently. Seems to me as if it fits well into damage repair, particularly in regard to the fixing of cell loss via epigenetic cell rejuvenation. They also claimed not to be interested in short therm financial gains but to bring this forward in the long run. Although I had hoped they would be a little more diversified in regard to the other 6 aspects of SENS, but as it is devide and conquer i think that’s fine too, to focus on one aspect only. Of course not all details are public knowledge right know, and who knows, perhaps they expand their portfolio in the future. I think it is definitively a big move forward as it will also attract more attention to the industry as a whole.

[Innomen]

This video justified subscribing and clicking the bell. The man is a legend for good reason. This talk is Jam Packed with important points.

[Thebusysuperhuman]

Been following you for years and so many people have benefited from your work and the knowledge you share. Keep going on your life’s purpose. Speaking as an ex scientist and you hit nail about capitalism and instant gratification in science

[euged]

i wonder if Google's Calico is, in reality, actually avoiding the "short-term-ism"

[longevityculture]

There is a hypothesis that the extracellular matrix stiffening is the cause of other hallmarks. The paper by Alexey Moskalev and Alexander Fedintsev last year was very interesting and I know they keep digging in this direction.