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PRP Therapy For Hair Loss - Will It Work?
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If you are looking for solutions to male pattern hair loss, chances are you’ve come across ads for Platelet Rich Plasma (PRP) therapy.
The term sounds straight out of Star Trek, but it’s actually a simple procedure.
And the ads often suggest that you’ll get hair regrowth straight out of science fiction.
But is this realistic?
In today’s video we’ll explain exactly what PRP is and how it’s supposed to treat hair loss, before turning to the million-dollar question: what are the chances it will work for you?
And if it does, what kind of results can you expect to see?
Stay tuned.
Timestamps
📌0:00 - Intro
📌1:07 What is PRP?
📌2:30 What is PRP used for?
📌3:30 PRP for hair loss.
📌4:24 How good is it, what is the evidence?
📌5:14 Literature reviews
📌7:00 Meta-Analysis
📌7:49 Percentage of the PRP Responders
📌8:46 Is PRP worth it?
📌10:52 Conclusion
Full Transcript
WHAT IS PRP?
So blood is made up of two major components: the cellular part which contains cells like red blood cells etc., and the fluid part or plasma.
The plasma consists primarily of water and proteins.
To make plasma, you put a blood sample into a device called a centrifuge and spin it at high speed.
This separates the blood into its cellular and plasma components.
To prepare PRP, after you’ve spun the blood, you use a special syringe to extract the platelet-rich portion of the plasma.
Platelets are the component of blood that allows it to clot, like for example when you get a scrape or a cut.
Now due to the way PRP is prepared and extracted, it contains a much higher greater concentration of platelets relative to whole blood: between three to seven times higher.
After the application of local anesthetic, the PRP is then injected into the balding area of the scalp.
PRP is broadly classed as a regenerative medicine practice.
It is based on the idea that the high-density platelets deliver a variety of growth factors to the scalp.
And these growth factors prompt the body to heal itself through stem cell regeneration and soft tissue remodeling.
These growth factors are contained in the 40-80 organelles which are in each platelet and are called alpha-granules; when these are activated the growth factors are released.
WHAT IS PRP USED FOR?
It’s important to understand that PRP was not developed specifically for hair loss AGA.
It goes back half a century and was originally developed for use in hematology patients.
Then surgeons picked it up, and starting using it to facilitate various kinds of surgery.
Today it’s used to accelerate healing in other dermatological conditions like ulcers, vitiligo, acute traumatic wounds, as well as musculoskeletal injuries and problems with tendons and ligaments.
Despite the fact that PRP is only administered by doctors, it’s a bit controversial among the medical community.
The crucial point involves the relative lack of clinical data.
As well as the fact that we don’t understand exactly how it works.
But perhaps the most important issue is the lack of standardization.
In other words how wildly different the treatment protocols are from one clinic to the next, which we’ll discuss this below.
This has led some medical bodies to view it as the quote “wild west” of regenerative medicine.
PRP FOR HAIR LOSS
PRP is thought to promote hair growth via
a) increasing the survival and proliferation of hair follicle cells,
b) stimulating follicles to transition from the resting to the anagen growth phase of the hair cycle, as well as c) prolonging the anagen phase.
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