Why human brain cells grow so slowly

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Growing human neurons in the lab can be a time-consuming process. Some cortical cells take years to reach maturity - many times slower than the equivalent cells in a mouse. Researchers have been exploring some of the mechanisms that could be behind these very different timescales of growth - and have found a kind of epigenetic ‘braking’ effect that slows maturation. Manipulating this ‘brake’ could allow scientists to speed up the study of older brain cells in a dish.

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What does this mean for the overall lifespan of the neurons though? If they can modified to mature sooner for faster research, does that also mean they will also age faster and hit their Hayflick limit sooner?

PaigeWylderOwO
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Great video explanation. I found the epigenetic regulation animation particularly fascinating; I suppose the question is, there must be a reason why the cells are inhibited from faster growth, any preliminarily ideas of why that is?

deadwalking
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But what is the significance of epigenetic mark?

deveshgupta
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This woman's mic is dripping with saliva...thufferin thuccotash

JohnComeOnMan
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Basically what I’m getting from this video is without God your brain can grow faster? Epigenetic is a metaphor of God.

mzberryembooberry
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can it allow a person to become smart?

mrtienphysics
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Why do they care it’s not like they’re creating new beings in a lab. Or are they.

kforest
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Stimulate these cells with youtube video every day, they will grow fast!

albertwang
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Worst explanation Ive heard in a while.

whitemale
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As interesting as this sounds, I am skeptical about the applicability of this system as a human neuronal model. Even growing neural stem cells in culture induces countless artifacts.

Now you want to accelerate the aging process? These cells will simply become less "human" over time.

JL-nbyc
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Nobel Prize material! Congratulations!

alinstoi
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Why is growth speed hindered though?
What's the trade off?

oh_rhythm
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See, I'm not an idiot, I'm just very efficient at protracting the epigenetic maturation of my neurons.

Baalaaxa
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Give a big thanks to lab mice everywhere for their sacrifice in the name of science.

ktefccre
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If your brain cells grow slowly it doesn’t mean my brain cells grow slowly too. Keep your insecurities to yourself buddy

thegodofmoneymaking
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Clickbait title. Video answered how but not why

masterchiefer
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So, this video reveals a potential secret of prodigy!

footfault
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Faster growth more possibilities of mutations or cancer

RMN