Cardiac Output | CVS Physiology | Frank Starling Law | Regulation of Cardiac Output Physiology

Cardiac Output is One of the Most Important Topic in CVS Physiology/ Cardiovascular System. I have tried making it easy covering all aspects - Basics to Homometric, Heterometric Regulation ! A Must Watch for every 1st Year MBBS,BDS,BPT Students.
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[AkshatJuneja]

Celebrate 100 Videos & Share with your friends to help them too !
Thank You !

[nandinigoyal]

The drug used for heart failure is Digitalis, it inhibits the Na+K+-ATPase, which leads to increase in intracellular Na+ and subsequent decrease in Ca2+ efflux, which causes higher contractility.

Sir, many congratulations to you on this big achievement! Your channel is undoubtedly my favorite, all the videos and short and to the point. They do not become long and monotonous.

[sonaligehlot]

Digitalis used to treat heart failure as it inhibits na+k+pump
And increases intracellular na+ and ca2+ and have positive inotropic effect i.e.increased force of contraction

[himanshuambilkar]

Cardiac output
Cardiac index
Control of heart rate extrinsic autoregulation.
Control of stroke volume intrinsic regulation.
Heterometeric regulation-
Preload
Afterload
Frank starling law.
Venous return-
Thoracic pump
Cardiac pump-
Via A tergo
Via A frontae.
Muscle pump.
Total blood volume
Capacity of venous return
Body position
Pathological.

Homometeric-
Catecholamines - b1 adrenergic receptor.
Digitalis.
Vagus nerve
Heart failure
Depressant- quinidine
Procainamide
Barbiturates.

Thank you sir

[jaikumar-gtsd]

Sir great work but tg link is not working?

[SS-hjdl]

drug used in heart failure is digitalis, it inhibits sodium potassium pump, since Na+----K+ pump pumps 3 Na+ out and 2K+ in is inhibited so intracellular Na+ increases...( gradient of Na+ from outside to inside is decreased )
there is another exchanger called sodium calcium exchanger through which sodium is taken in and calcium is taken out...
now since Na+ gradient from outside to inside is decresed, this will decrease activity of sodium calcium exchanger and calcium conc. in cell increases that cause increase myocardial activity
am i right sir...

[riddhipatel]

Digitalis is the medicine for heart failure
Because due to inhibition of Na - K ATPase
Na+ influx increases causing decrease in Ca efflux leading to contraction of myocardium and increase in stroke volume

Congratulations sir 💐

[shilpasenta]

Congratulations 🎊 🎊 🎊 you are amazing, , and you deserve this success

[debiprasadbisoyi]

Digitalis.
It inhibits Na-K ATPase, as a result Na+ efflux is decreased, to compensate it intracellular Ca+2 is increased, ....which increases heart rate, simultaneously cardiac output

[arshiyakhan]

Digitalis used to treat heart failure
Mechanism: inhibits Na+ - K+ ATP ase activity in myocardium which increases Na+ inside the cell and also decreases Ca2+ efflux so increases Ca2+ inside the cell..causes positive inotropic effect that is increase myocardial contractility.

[mbhardwaj]

Sir what is the difference between surface anatomy and surface marking with explanation plz

[riteshchaurasia]

14:58 if u could explain why in heart failure the cathecholamine decreases, does heart too synthesize cathecholamine..

[riyadwivedi]

Heartly congratulations sir for ur 100. Sucessful videos keep going

[chinnamvenkatesulu]

Digitin is used, it inhibits Na+ k+ATPase so Na+ remains intracellular because of this ca+2need not go outside so ca+2 efflux is decreased and it increases contractility of heart

[deepakkumarnagpure]

Thank you sir, it's very helpful to us 💯

[patelaayush]

Can I write in exam paper in the same way?

[nehaattar]

Thank you so very helpful at the last moment preparation.. understood very well....

[priyankajhajharia]

Very well explanation 👌sir more videos uploade on CNS

[chrintsavi]

Thank you so much....highly informational

[shiva]

Sir if homometric regulation comes under intrinsic autoregulation then in this why external factors like nerves and catecholamines are involved