AlphaFold 3 AI Just Won The Nobel Prize!

📝 Check out AlphaFold 3 here:

📝 Or try it out through AlphaFold server for free:

This video was made in partnership with Google DeepMind.

My paper on simulations that look almost like reality is available for free here:

Or this is the orig. Nature Physics link with clickable citations:

🙏 We would like to thank our generous Patreon supporters who make Two Minute Papers possible:
Alex Balfanz, Alex Haro, B Shang, Benji Rabhan, Gaston Ingaramo, Gordon Child, John Le, Kyle Davis, Lukas Biewald, Martin, Michael Albrecht, Michael Tedder, Owen Skarpness, Richard Sundvall, Taras Bobrovytsky, Ted Johnson, Thomas Krcmar, Tybie Fitzhugh, Ueli Gallizzi.

#AlphaFold3 #AlphaFold

[Hitjuich]

Alphafold changed bìotechnology forever. This is huge! Looking forward to working with the new version

[itsjusttmanakatech]

I wasn’t impressed until I heard AlphaFold had implemented Dark Mode. What a time to be alive!

[Favmir]

4 minutes earlier than the official Google deepmind channel? That was indeed fast, you're right

[johnjones]

This is Nobel prize, Turing award level work and “Dark mode!” Life is strange.

[realmetatron]

Version 4 can fold your laundry. Version 5 can cut onions without crying.

[Sashik]

Oh I'm holding onto my papers now

[merlijnfolkerts]

Stuff like this saving lives is why i am going to study artificial intelligence when im out of highschool

[ElOroDelTigre]

I'm around 50 now and seeing that the field I love is doing real change (not in a "generating revenue" way, but in actual "improving humankind" way) brings a tear to my eye. Maybe a 20-something years old kid does not realize how big this is, but for me it is, truly and marvelously, an amazing time to be alive. Gives me a bit of hope that before I kick the bucket I'll get to see some of that utopian advancement and eradication of diseases we used to dream about.

[PranavPunuruFilms]

i'm pretty sure they're participating in CASP16 because of this. My lab is participating too. We just agreed that they've already won

[Rajivrocks-Ltd.]

Everyone is talking about LLMs, But this is really where impact to the future is being made!

[kaspernordlund]

I get shivers every time i work with alphafold! to think that it is free. A true testement to the Greatness of human civilisation!

Bet AplhaFold 6 will be folding reality itself 😎

[larrychanhangpei]

You made me love papers and start reading it. It means a lot to me and thank you for the excellent work as always!

[bloodbound]

I LITERALLY Made a 5-page paper.. on mealworms specifically superworms that broke down plastics and got calories from them and were able to reproduce from the plastic diet thanks to their enzymes. Finally, this is getting attention, making those enzymes into like an artificial stomach to at least turn plastics into Glycol is better than nothing!

[azrael]

ChatGPT was fancy. Now this. This is revolutionary.

[projectarduino]

If a protein can be manufactured to repair human dna, or to recover damaged telomeres, that would probably one of the most impactful biomedical results of all time. To help the elderly regain their strength to live healthier and longer lives by reducing cellular damage and cancer risks would be profound.

I recently lost my grandfather because of age related weakening and loss of autonomy. If something like an enzyme injection could have kept him more autonomous by keeping his fatiguing body healthier, he might even have been alive today.

I lost all my other grandparents to cancer, so if dna repair could help inhibit cancer development from mutation, it would be amazing to see no one ever have to go through what I have gone through again.

[Rkcuddles]

Absolutely love these longer videos. Can’t get enough of your enthusiasm and the paper news

[EVILBUNNY]

I can imagine a system that can sequence your personal genome and through tons of training be able to discern how exactly you’ll react to certain drugs and what dosage you need. It’s crazy to look back at how far Medicine has come in the last 20 years, it’s impossible to even begin to image the capabilities in another 20 years time.

All advancements start somewhere, and releasing a paper is usually always the first step

[cureadvocate]

Seeing AlphaFold 3 design ligands to help the brain and spinal cord regenerate would be cool, as myelin (and a few other tricks) inhibit neural regeneration

Another interesting use case: exploring SIRT6 variations, its impact on aging, and finding ways to enhance its functionality.

[lacklvster]

im so glad that i was born at JUST the right time to enter college for biotech in the infancy of all these new programs. cant wait to actually work with them later in life