Vitamins D and K2

Latest on Vitamin D

Basically, consider 400 units (10 mcg) per day

But, NHS mid Essex

Routine screening of vitamin D levels and prescribing of Vitamin D is not advisable.

Both clinical symptoms and risk factors must be present before measuring Vitamin D levels (25OHD).

As yet there is no clear evidence to prove the risks from non-symptomatic Vitamin D deficiency.

Adults

Vitamin D levels less than 30nmol/L (12ng / ml)

Oral capsules, 40,000 units (1,000 mcg or 1 mg) colecalciferol weekly for 7 weeks

(400 units per day = 2,800 units per week)

Vitamin D levels 30 – 50 nmol/L (12 – 20 ng / ml)

Buy your own, 400 units per day

Vitamin D levels more than 50 nmol/L (20 ng / ml)

Buy your own, consider, 400 units per day

Vitamin K1

Phylloquinone

Involved in blood coagulation (1929)

Found in plant foods like leafy greens

Vitamin K2

Menaquinones

Mostly bacterial origin

Animal-based and fermented foods

Adult vitamin K Adequate Intakes, 90 -120 mcg

Fermented foods

Sauerkraut

Natto

High fat dairy from grass fed cows

Eggs

Animal organs

Gut bacteria

Antibiotics

Vitamin K might play a role, osteoporosis and coronary heart disease

Vitamin K-dependent proteins

Vitamin K2 supplements may improve bone and heart health, while vitamin K1 has no significant benefits

Promotes bone calcification

Three-year low-dose menaquinone-7 supplementation helps decrease bone loss in healthy postmenopausal women

May prevent tissue calcification

Tissue-specific utilization of menaquinone-4 results in the prevention of arterial calcification in warfarin-treated rats

Vitamin K2 (MK-4) reduced blood vessel calcification whereas vitamin K1 did not

Dietary intake of menaquinone is associated with a reduced risk of coronary heart disease: the Rotterdam Study

K2 may help with dental health

Especially with vitamin D

Links with liver cancer

Links with preventing advanced prostate cancer

Dietary intake of vitamin K and risk of prostate cancer in the Heidelberg cohort of the European Prospective Investigation into Cancer and Nutrition (EPIC-Heidelberg)

Synergistic effect with vitamin D

Vitamins D and K as pleiotropic nutrients: clinical importance to the skeletal and cardiovascular systems and preliminary evidence for synergy

Prevalence of hypercalcemia related to hypervitaminosis D in clinical practice

Determine the concentrations of 25-OH-vitamin D at which the risk of hypercalcemia

N = 25,567

Hypervitaminosis D was defined at serum 25-OH-vitamin D more than160 nmol/L (64 ng / ml)

Results:

382 samples were identified as the first record of hypervitaminosis D

39 presented hypercalcemia (10.2%)

Some had 25-OH-vitamin D levels between 161 and 375 nmol/L.

(most subjects presented hypercalcemia at serum concentrations of 25-OH-vitamin D less than 375 nmol/L, 150 ng / ml)

In 15 subjects, hypercalcemia could be directly attributed to vitamin D

In no case, serum calcium achieved concentrations considered as critical values (more than13 mg/dl).

Conclusion

Hypercalcemia due to vitamin D represented less than 4% of the total hypervitaminosis D detected

Less than 0.1% of the tests performed.

Healthline

No strong evidence proves that moderate amounts of vitamin D are harmful without an adequate intake of vitamin K. However, research is ongoing, and the picture might become clearer in the near future.

[davejohnson]

I'm a community pharmacist and often recommend your videos for clinical information. You're what the Internet was made for. Kind regards

[AShasa]

I had my yearly checkup in June. It went as it typically does until we got to the blood work. My doctor was telling me the blood work she was ordering and she had not mentioned vitamin D. I asked her why we were not checking my vitamin D levels and she said they don't. If they checked it at some point previously (prior years) and the patient was deficient they would have been told to take it and if they took it their numbers would be better, if they didn't it would not. No need to check it. I said 'Isn't there a relationship between a person's vitamin D levels and how bad COVID-19 does you?' She said yes. So during a pandemic that has killed a number of people why wouldn't doctors as a practice check for a deficiency in their patients that could potentially save them if they get COVID-19? That does not make sense to me. This pandemic has opened my eyes about the healthcare industry.

[drkarenswrld]

I’d lived in Chicago for years, always low Vitamin D levels. Moved south, but levels didn’t rise much, though I was taking about 2000 in/day sporadically. Doc told me this was plenty. Because of these videos, I began taking D religiously. After about 3 months of this, I realized I was sleeping really well and much less depression. Doc confirmed normal range. When I went to get new supply, I realized I’d actually been taking 10, 000 iu/day! That’s the dose it took, but no doc had taken me seriously. Thanks to these videos encouraging us to keep up levels!

[markgray]

Just an update, in 2009 I was living in MA - USA, my levels of D3 were nonexistent and every winter I got the flu and whooping cough, my doctor put me on D3 and I have not been sick since. I also added K and Zinc to my daily consumption. I live in a retirement community now in Florida and many folks around me did get COVID and many were hospitalized and some died, I did not get sick and I was exposed to many who did get this flu. I recommend D3, K and zinc to all my friends and some are now doing this as well.

[RiceSteph]

I went to my GP with extreme exhaustion, anger issues, up and down in emotion, and feeling borderline depressed. I thought it was baby blues or postpartum depression, but she checked my blood for vitamin d and said my numbers were through the floor. Prescribed me 50, 000 IUs/week for 3 months and it was life changing! From the first 30 mins I took the first pill I felt instantly better. No more falling asleep behind the wheel (literary, I had to pull over the road to sleep smh). My previous doctor had given me anti depressants without checking for vitamin D. I wish docs would check for Vit D before prescribing anti-depressants.

[msb]

Hi Doctor Campbell, am pleased to inform you that I have watched your videos on pharmacology and physiology and I have passed all my written exams for my nursing course. Thanks very much sir for your teaching videos.

[bbhdd]

This man is a national treasure. This whole channel needs to be archived and immortalized. John, I encourage you to ask your followers to do this. It’s possible for someone to make a website and download and transfer all of your videos to an independent website so we don’t lose all of this invaluable information. :)

[mrbigsdaddy]

A very important topic came up here. Probably far more important for people to understand than Vitamin D. The notion that Saturated fat/ cholesterol causes heart/arterial disease has lead to catastrophic decline in human health. We have been told to reduce sat fat and red meat in the diet, and replace it with processed grains and industrial fats refined from otherwise inedible seeds, soybeans and such. The result is a diet low in protein, high in processed carbohydrate, and sky high in omega 6 fatty acids. Those guidelines havent worked out well. There is you causation for diabetes, heart disease, obesity, weak immune systems, many cancers, and more. Eat whole foods people. I didnt say whole grains did I? No, and I didnt say go plant based either. That is all highly profitable crap. Optimal for me is something like Beef butter, eggs,

[billydoyle]

I have to applaude this one more than others John. Bravo mate. You've reduced mortality by massive amounts if just 1% of your subscribers takes action on what they've learnt from you.
Awesome!

[cindybogart]

This is the best information on vitamin D &K2 I have ever heard. Not even my Dr. could touch on these concepts. Thanks, Dr. John for all you do to help keep us informed. It’s extremely valuable & appreciated!💫

[kristiblack]

Taking Vit D & K has completely changed my health for the better. Rarely to never sick, sleep well and hormones are much more balanced. Best insider advice I ever got working in the surgical field for 15+ yrs. Plus Iodine and it's a game changer! Thank you so much Kind Sir, for you are much appreciated, cherished and respected!

[erictheviking]

Thank you dr Campbell, I must say Im 68 years of age... I have had some peripheral neuropathy in the soles of my feet and the cool draft feeling on my calves for a few years, my blood sugar is fine, I eat very little sugar... I started supplementing with K2(mk7), D3 and magnesium four months ago...I now suffer very little cold draft feeling over my calves and have regained about 50% of feeling back in the soles of my feet so far

[andrewhaire]

His lecture on the heart philology is brilliant. Having had an aortic valve replacement 35 years and tried to understand the working of the heart. He’s the only lecturer that give clarity! Clarity ! Clarity, genius!

[joyfulpreterist]

I take 5000u of D3 and 800mcg of K2. Doing so for 2 years absolutely no problems. Mainly because it is a combo dose put out by Piping Rock. Havent had the flu for 5 years or been to the dentist for same time. Bone density at 100% at age 79. Still work in busy surgical ward in a hospital.

[barbvdvelde]

I’m so admiring of the way you explain so many complex issues in such a clear easily understood manner John. Have recommended you to many. Much gratitude to you, you’re providing such an incredible service for us all. 🙏🏼

[marymcmann]

I take 4000 units of vitamin D. My Dr always includes a check of my Vitamin D levels in my bloodwork because a few years ago I was deficient. Thank you for your very informative videos. I learn so much from them. I’m a 78 yo woman trying to stay as healthy as my family elders who died in their 90’s and 100’s. It’s never to late to learn!

[tracyheaslip]

Going back about 20 years there was a guy in Edmonton that his 17 year old son came down with MS. The Globe and Mail in Toronto Canada covered the story. The father was a geologist I believe. He decided to study the world and discovered that anybody around the equator did not come down with MS or diabetes, he contributes it to lack of vitamin D. He put his son on 4, 000 units of vitamin D a day and his Son never had another MS attack.

[daniel]

What I've learnt is that Vitamin K2 helps removes calcium in the soft tissues and puts it into the bones. While you are taking vitamin D your calcium absorption is increased by 20x so making sure that you reduce your calcium (dairy) intake, at the same time make sure that you are taking 100mcg of K2 per 10, 000iu of Vitamin D, drink 2 litres of water a day to reduce the formation of kidney stones and take Vitamin D with a Fat, either a fatty meal or I take it with a high strength Omega 3 and fish oil tablet as Vitamin D is a fat-soluble vitamin and is absorbed better with healthy fats.

[jackieb]

Your knowledge never ceases to amaze me Dr John! Thank you for sharing all your knowledge 🙏🏻

[annaandi]

Dr. John -- Thanks for helping us to stay healthy. Keep up God's work! We love you and check for your updates every day. You are amazing! Thanks for all that you do!