DNA methylation

This video explains the process of DNA methylation and its importance in eukaryotic transcription using DNA methylase and Histone methylase enzymes.
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[wesG]

This was a very helpful lecture, thank you.

For when I inevitably revisit this video, or for the sake of others, here are some time stamps:

0:00 Introduction
1:25 DNA Methylation
3:23 CpG Islands
5:42 Role of methylases/different types of DNA methylation
10:56 Methylation and transcription
14:54 Cross talk between methylation and acetylation
17:08 Gene insulators as gene silencers
20:36 Role of an insulator - genomic imprinting
26:19 Protein (histone) methylation
29:52 Coupling histone methylation and DNA methylation
34:10 Heterochromatin and euchromatin silencing

[Vishal]

You are really born to solve life science problems. Thanku

[PreetKaur-fkds]

I would like to thank you for the video, which saved my darn important time. saw your video and then did a quick reading... the concept is clear. Thanks, thanks thanks

[LS-ugxf]

I like all of your videos. Very informative and clear. Please could you do a video on CpG oligodeoxynucleotides.

[zoltankhani]

I am a self learner , familiar with DNA RNA , RECENTLY CAME ACROSS WITH. METHYLATION which looks very interesting
Reviewed a lot of lectures , understood them partially, now I am left with some questions about why methylation happens, is that the only factor for cancers
What is the difference between. The sequential mutation and methylation ending to mutation any reply is greatly appreciated .an old time student

[hanithraj]

Dna methylation - Turns off transcription
Histone acetylation - Turns on transcription
But as the Histone methylates, whether the transcription turned on or off ?? What happens when histone prtn methylates??

[ikastrati]

Thank you so much for all your videos. Could you make a video on cell signalling, MAPK ie ERK Pathway, please?

[manojmahajan]

excellent talk..complex topic simplified in lucid manner..thanks a lot

[msmikymiks]

this lecture was very helpful...omg..i have a better understanding now...thanks a million!!!

[swetasagarikaamanta]

Lecture was so helpful. Thank you sir.

[oluchiibegbu]

I find this video very useful. I now understand the topic better. Thank you

[nitinchalla]

Thank you so much, Sir, this helped me a

[LACERENZANUTRITION]

Good morning, a question please, in practice does hypermethylation or hypomethylation predispose to tumors? Thanks

[kweuig]

Methylation of CpG occurs in CpG poor regions and CpG rich regions (CpG Islands) of the DNA are seemed to be protected from methylation (Lim, Maher 2010). 
Please clarify if CpG are really hotspots???im confused

[MaDlY]

video is too good, , thank you sir for this video..

[akhil]

Would you please explain what is the MBD2 protein size, binding/active sites and how many DNA probes can binde with one MBD2 protein..??

[akhil]

Hi.. bro... Can you provide the references of your video..?

[sukrishnatk]

Could you please make a video of how to identify the genes promoter region and methylation status in the promoter regions by different software?

[kaushanichanda]

Can you please make a video on dna methylation in bacterium (prevention of self dna from restriction enzymes)

[bonk]

Read this pls..i just took a tetanus vaccine and it has differential extraction-methylation CAN THIS CHANGE MY DNA ?