Brain Organoids Communicate: A Step Toward 'Organoid Intelligence'

Scientists have connected two organoids together with an axon bundle, to study how brain areas communicate. They sent signals back and forth and responded to external stimulation. This could be a step toward biocomputing.

Learn about: axons, white matter, re-entry, optogenetics, myelination, entrainment, short-term potentiation

CORRECTIONS/CLARIFICATIONS:
As the pinned comment points out, there are many different kinds of neurons, and two pairs of organoids may not have the same cellular makeup. This natural variation between neurons might also account for the different post-stimulation behavior of the organoids from different cell lines.

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Osaki et al., 2024: Complex activity and short-term plasticity of human cerebral organoids reciprocally connected with axons

[MrKoffeeKup]

There are actually quite a few thousand different types of brain cells so its very likely we are growing very different organoid clusters even if they all look the same.

[popkinbobkin]

listen man I like those brain organoid guys, maybe they're not the brightest you know, but they seem really chill, like playing pong, driving robots, firing synchronically, having fun and stuff. the only thing that separates them from my buddies now is that they don't drink beer yet. definetly would hang out

[alkeryn]

that myelin sheath watercolor is amazing!

[thezikaz]

So glad youtube put this video in my recommended videos. Subbed, Rang, Liked!

[rayrocher]

The abilities to cure paraplegic, Handicap people, soon Walk and live better more. Freedom of movement, amen great work

[IhmHomeFarm]

This is great work! And you kind of match the neurons🙂.

[GeoffryGifari]

Is organoids building a network the most likely outcome?
If you give them the chance would they definitely connect with each other?

[Azyraasr]

The brain revolution is the next cheap sci-fi trope

[Fiendformusic]

Do you want skynet, because this is how you get skynet?

[AWICKEDVIXEN]

How can all these organoids live without blood supply thats the question

[ONDANOTA]

Let's remove an arm. Are you still a person? Yes, you are. Same for legs, liver, eyes etc.
Let's remove a brain. Are you still a person? No.
Hence a brain organoid is a person to me. With human rights and everything

[therealsmellystudios]

My homunculus
"What is my purpose"
Me
"You swipe youtube shorts"

[A-juv]

This was so easy to digest as a layman, incredible work! The potential implications of the mentioned “bridge” and the “stimulation synchronization” are so relevant to my work in software integration. I have been thinking all week about how much of “integration” boils down to unfurling the meaning of “communication”, and have been trying to draw from nature as much as I can. I would be so fascinated to hear the findings of this study applied to our understanding of Synesthesia.

[JNJNRobin]

its all fun and games until an organic computer becomes sentient

[GeoffryGifari]

Seems like digital computer, new analog computer, and brain organoids are gonna converge

[Rik]

This is absolutely fascinating. I was just thinking about how the "emergent property" theory of consciousness, or of anything really, is just empty metaphysics unless a mechanism, increasing complexity for instance, can be found to account for the property in question. And example of this is the recent niobium-titanium-tantalus alloy that is durable at both extremely high and extremely low temperatures: this was completely unexpected, i.e., an "emergent property".. However, an explanation was found in the crystalline structure of the alloy.

So maybe, as these experiments with organoids and axons progresses with the addition of more connected organoids, some progress may be made in the (distant) future as organoid complexes approach the billions and eventually even trillions.

This won't be in my lifetime, of course; I'm 71.

[demo_AAA]

This makes me imagine a future that looks like Scorn, the video game. Can’t wait for meaty computers to phase out the weak silicon ones.

[Tracing]

I can't wait for my personal humunculus maid.

[DonChocolatey]

If this information is available to the public I would assume the government is about 10-20yrs ahead.

[rocklobster]

Oh you don't know?
I know.
You end up with a torture revenge computer like AM from "I have no mouth and I must scream"

I think....

Therefore
I AM