Does the epigenetic clock play a causal role in aging? | Steve Horvath

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Although epigenetic clocks clearly *relate* to causal aspects of aging, scientists don't know if the clocks are inherently causal. At this time, the clocks are not validated for use as clinical biomarkers for individual use, but rather to look at trends across larger studies. The methylation patterns appear with age occur in polycomb group protein target regions that play a role in regulating stem cells. In this clip, Dr. Steve Horvath discusses whether epigenetic clocks play causal roles in aging.

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Original episode posted December 22nd, 2020.
#GrimAge #aging #biomarker

About FoundMyFitness: Rhonda Patrick has a Ph.D. in biomedical science from the University of Tennessee Health Science Center, and St. Jude Children’s Research Hospital. She also has a Bachelor’s of Science degree in biochemistry/chemistry from the University of California. She has done extensive research on aging, cancer, and nutrition.

It is Dr. Patrick’s goal to challenge the status quo and encourage the wider public to think about health and longevity using a proactive, preventative approach.

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