No one can technically win against Wesker, but the characters have plot armor
martinlacunza
Leon + player control = solo all RE verse
Lord_Cheems
To be honest if wesker didn't die in Resident Evil 5 he will be a walking hell on earth for Chris, Leon and also other protagonist. knowing him can be a perfect mutant with every virus type is nightmare
elgamkv
Me in RE4 with infinite rocket launcher : 💀 Time to die
Lexors
Leon: "let me introduce my secret Anti-Bio Weapon"
Leon: *Shows Ashley with Xboom *
AmandeepSingh
Chris: don't worry Leon accept the warm loving embrace of my sister as you continue the Redfield blood line while I'll deal with-
Albert: Ah Chris it's been awhile how's Jill, heh
Chris: Wesker..
twinsaiyans
Without plot armor, NO ONE can beat Albert Wesker
kaipark_x
I think experience should actually go to wesker hes been there longer than leon has been and hes been in just as much if not more fights then leon lore wise not just what's in the games/cgi movies
vikingplays
Leon literally sends everyone else to the shadow realm except Wesker
dumitruoproiu
A good moment to remind ourselves that Chris punched the brick wall also known as Albert Wesker without breaking his fists.
FireFist
I mean man wesker is pretty much a fucking bio weapon superhuman, even tho Leon Is gi joe he's still a regular human LMFAOOO
falconreplays
I've never played the Resident Evil games but I've come to the assumption that Albert Wesker is the most powerful villain in the series by a long shot, is that a reasonable assumption?😂
jaonplx
Wesker was the pinnacle of Resident Evil viruses, literally. There is no better Bio weapon than him. The perfect balance of superhuman abilities while retaining his intellect and humanity.
If he didnt die to plot amor he would solo the entire RE heroes if he really wanted to. One could argue that his down fall was his ego and that he played with his food for too long, but nah, it was plot amor what killed him. He the GOAT RE villain.
alexferrier
Leon: I am above you all!
*Wesker laughing in the background*
cheezit
*I pretty much figured Leon would get annihilated if he played as main character in RE 5 game for 2 reasons :*
*1) Leon mostly works alone while in contrast Chris works in team always giving him team power advantage*
*2) Leon may be more skilled or agile, but Chris is much stronger and his punches hit harder. Chris punched a freaking huge boulder into lava not feeling any pain but when everytime he punched Wesker his hands have shown to hurt (hence, Wesker's skin is harder than rock)*
JackFrostIsHere
"Wesker win low/mid diff"
(Leon): ITS OVER WESKER, I HAVE THE POWER OF THE PLOT IN MY SIDE!
darkenmishima
My two favourite characters.. Leon S. Kennedy and Albert Wesker...
Speaking Experience, it should be Wesker...
And yes, Wesker wins...
jcxu
Leon will forever be my favorite hero and wesker will always be my favorite villain
ThEXperiment
Vendetta leon would really have a hard time against re5 Wesker but it would be close and go either way
Dylan-qjgj
Wesker: seven minutes is all i can spare to play with you